In this article, a series of betulinic acid derivatives (3a∼ 3u, 4a∼ 4e) were synthesized
through a stepwise structure optimization and evaluated for their anti-α-glucosidase …

This review comprehensively describes the recent advances in the synthesis and
pharmacological evaluation of steroid polyamines squalamine, trodusquemine, ceragenins …

Medicinal plants have been used by humans since ancient times for the treatment of various
diseases and currently represent the main source of a variety of phytocompounds, such as …

The hydrophobic and the hydrophilic rims in the active site of human carbonic anhydrase IX
(hCA IX) which as well contains a zinc ion as part of the catalytic core, were simultaneously …

Inhibiting the intestinal α-glucosidase can effectively control postprandial hyperglycemia for
type 2 diabetes mellitus (T2DM) treatment. In the present study, we reported the binding …

A series of novel cyanopyrimidine-hydrazone hybrids were synthesized and characterized
with various spectroscopic techniques. The synthesized compounds were tested at NCI …

A series of A-ring modified oleanolic and ursolic acid derivatives including C28 amides (3-
oxo-C2-nicotinoylidene/furfurylidene, 3β-hydroxy-C2-nicotinoylidene, 3β-nicotinoyloxy-, 2 …

Pigments have been used since historical times and are currently used in food, cosmetic,
pharmaceutical, and other industries. One of the main sources of natural pigments are plants …

Malignant melanoma is one of the most pressing problems in the developing world. New
therapeutic agents that might be effective in treating malignancies that have developed …

Modern pharmacology studies have demonstrated that α-glucosidase is closely associated
with a variety of metabolic disorders. Natural herbs have emerged as possible sources of α …