Acupuncture and electroacupuncture (EA) as complementary and alternative medicine have
been accepted worldwide mainly for the treatment of acute and chronic pain. Studies on the …

Human angiotensin-converting enzyme-related carboxypeptidase (ACE2) is a zinc
metalloprotease whose closest homolog is angiotensin I-converting enzyme. To begin to …

The novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has emerged to a
pandemic and caused global public health crisis. Human angiotensin-converting enzyme 2 …

The third edition of this monograph continues to have the goal of providing an overview of
current thought about the spinal cord mechanisms that are responsible for sensory …

Motivation: New relationships are often implicit from existing information, but the amount and
growth of published literature limits the scope of analysis an individual can accomplish. Our …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of COVID-19, is
reported to increase the rate of mortality worldwide. COVID-19 is associated with acute …

Release of endogenous dynorphin opioids within the spinal cord after partial sciatic nerve
ligation (pSNL) is known to contribute to the neuropathic pain processes. Using a …

Acid-sensing ion channel 1a (ASIC1a) promotes neuronal damage during pathological
acidosis. ASIC1a undergoes a process called steady-state desensitization in which …

The κ-opioid receptor (KOR) is an attractive target for the development of novel drugs. KOR
agonists are potentially safer pain medications, whereas KOR antagonists are promising …

Spinocerebellar ataxias (SCAs) are dominantly inherited neurodegenerative disorders
characterized by progressive cerebellar ataxia and dysarthria. We have identified missense …