Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

D Niu, HJ Wei, L Lin, H George, T Wang, IH Lee… - Science, 2017 - science.org
Xenotransplantation is a promising strategy to alleviate the shortage of organs for human
transplantation. In addition to the concerns about pig-to-human immunological compatibility …

[HTML][HTML] Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics

J Shao, W Fan, B Ma, Y Wu - Molecular medicine …, 2016 - spandidos-publications.com
Identification and isolation of breast cancer stem cells (CSCs) based on CD44/CD24
expression and/or enzymatic activity of aldehyde dehydrogenase 1 (ALDH1). However, the …

Anticancer activity of a monobenzyltin complex C1 against MDA-MB-231 cells through induction of apoptosis and inhibition of breast cancer stem cells

S Fani, B Kamalidehghan, KM Lo, SE Nigjeh… - Scientific reports, 2016 - nature.com
In the present study, we examined the cytotoxic effects of Schiff base complex,[N-(3, 5-
dichloro-2-oxidobenzylidene)-4-chlorobenzyhydrazidato](o-methylbenzyl) aquatin (IV) …

[HTML][HTML] Virome characterization in serum of healthy show pigs raised in Oklahoma demonstrated great diversity of ssDNA viruses

WP Paim, MF Maggioli, MN Weber, G Rezabek… - Virology, 2021 - Elsevier
Abstract In the United States, show pigs are raised to compete in agricultural events. These
animals are usually raised in small herds with extensive human, domestic, and wild animal …

MnTE-2-PyP Suppresses Prostate Cancer Cell Growth via H2O2 Production

Y Zhu, EA Kosmacek, A Chatterjee… - Antioxidants, 2020 - mdpi.com
Prostate cancer patients are often treated with radiotherapy. MnTE-2-PyP, a superoxide
dismutase (SOD) mimic, is a known radioprotector of normal tissues. Our recent work …

Construction of a transposase accessible chromatin landscape reveals chromatin state of repeat elements and potential causal variant for complex traits in pigs

T Jiang, Z Ling, Z Zhou, X Chen, L Chen, S Liu… - Journal of Animal …, 2022 - Springer
Background A comprehensive landscape of chromatin states for multiple mammalian tissues
is essential for elucidating the molecular mechanism underlying regulatory variants on …

[HTML][HTML] ALDH1+ stem cells demonstrate more stem cell-like characteristics than CD44+/CD24–/low stem cells in different molecular subtypes of breast cancer

J Chen, S Liu, Y Su, X Zhang - Translational Cancer Research, 2020 - ncbi.nlm.nih.gov
Background CD44+/CD24–/low and ALDH1+ are both markers of breast cancer stem cell
(BCSC), we compared the biological characteristics of CD44+/CD24–/low and ALDH1+ …

[HTML][HTML] CD44+/CD24-/low 及ALDH1+ 与早期乳腺癌预后相关性比较

李芳华, 张晓 - 岭南现代临床外科, 2019 - lingnanwaike.com
目的比较CD44+/CD24-/low 及ALDH1+ 与早期乳腺癌预后的相关性. 方法回顾性选取我科2007
年4 月至2008 年2 月因早期乳腺癌行手术患者510 例, 收集其术后石蜡包埋肿瘤标本 …

[PDF][PDF] Somayeh Fani1, Behnam Kamalidehghan2, Kong Mun Lo3, Siamak Ebrahimi Nigjeh4, Yeap Swee Keong4, Firouzeh Dehghan5, 6, Rahman Soori5, Mahmood …

NM Hashim - anticancer drugs - academia.edu
In the present study, we examined the cytotoxic effects of Schiff base complex,[N-(3, 5-
dichloro-2-oxidobenzylidene)-4-chlorobenzyhydrazidato](o-methylbenzyl) aquatin (IV) …

[HTML][HTML] 不同乳腺癌干细胞亚群的自我更新和致瘤能力差异

邵军, 范威, 马彪, 吴毅平 - 肿瘤防治研究, 2015 - zlfzyj.com
目的分析原代培养乳腺癌细胞中不同乳腺癌干细胞亚群的自我更新, 致瘤能力差异.
方法采用流式细胞术和免疫荧光实验, 从乳腺癌原代培养细胞中分选, 鉴定CD44+ CD24-/low …