Therapeutic potential of AMPK signaling targeting in lung cancer: advances, challenges and future prospects

M Ashrafizadeh, S Mirzaei, K Hushmandi… - Life sciences, 2021 - Elsevier
Lung cancer (LC) is a leading cause of death worldwide with high mortality and morbidity. A
wide variety of risk factors are considered for LC development such as smoking, air pollution …

[HTML][HTML] Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis, prognosis and drug target discovery

Y Li, G Hou, H Zhou, Y Wang, HM Tun, A Zhu… - Signal transduction and …, 2021 - nature.com
Disease progression prediction and therapeutic drug target discovery for Coronavirus
disease 2019 (COVID-19) are particularly important, as there is still no effective strategy for …

[HTML][HTML] A novel signature predicts prognosis and immunotherapy in lung adenocarcinoma based on cancer-associated fibroblasts

Q Ren, P Zhang, H Lin, Y Feng, H Chi… - Frontiers in …, 2023 - frontiersin.org
Background Extensive research has established the significant correlations between cancer-
associated fibroblasts (CAFs) and various stages of cancer development, including initiation …

[HTML][HTML] Enhancer RNA SLIT2 inhibits bone metastasis of breast cancer through regulating P38 MAPK/c-Fos signaling pathway

P Li, Z Lin, Q Liu, S Chen, X Gao, W Guo… - Frontiers in …, 2021 - frontiersin.org
Background Breast cancer (BRCA) is the most common cancer in women, while the bones
are one of the most common sites of metastasis. Although new diagnostic methods or …

[HTML][HTML] Characterization of the tumor immune microenvironment in lung squamous cell carcinoma using imaging mass cytometry

R Li, Y Lin, Y Wang, S Wang, Y Yang, X Mu… - Frontiers in …, 2021 - frontiersin.org
Background Lung squamous cell carcinoma (LUSC) is a major subtype of non-small cell
lung cancer. The tumor immune microenvironment (TIME) affects the anti-tumor immune …

[HTML][HTML] A feature selection-based framework to identify biomarkers for cancer diagnosis: A focus on lung adenocarcinoma

O Abdelwahab, N Awad, M Elserafy, E Badr - Plos one, 2022 - journals.plos.org
Lung cancer (LC) represents most of the cancer incidences in the world. There are many
types of LC, but Lung Adenocarcinoma (LUAD) is the most common type. Although RNA-seq …

[HTML][HTML] Characteristic of molecular subtypes in lung adenocarcinoma based on m6A RNA methylation modification and immune microenvironment

H Zhou, M Zheng, M Shi, J Wang, Z Huang, H Zhang… - Bmc Cancer, 2021 - Springer
Background Lung adenocarcinoma (LUAD) is a major subtype of lung cancer and closely
associated with poor prognosis. N6-methyladenosine (m6A), one of the most predominant …

[PDF][PDF] Insight into the function of tetranectin in human diseases: A review and prospects for tetranectin-targeted disease treatment

S Iram, S Rahman, I Choi, J Kim - Heliyon, 2023 - cell.com
Tetranectin (TN), a serum protein, is closely associated with different types of cancers. TN
binds plasminogen and promotes the proteolytic activation of plasminogen into plasmin …

Plasma proteomics identify potential severity biomarkers from COVID‐19 associated network

AT Sahin, A Yurtseven, S Dadmand… - PROTEOMICS …, 2023 - Wiley Online Library
Abstract Purpose Coronavirus disease 2019 (COVID‐19) continues to threaten public health
globally. Severe acute respiratory coronavirus type 2 (SARS‐CoV‐2) infection‐dependent …

[HTML][HTML] Transcriptomic analysis of tumor tissues and organoids reveals the crucial genes regulating the proliferation of lung adenocarcinoma

X Ma, S Yang, H Jiang, Y Wang, Z Xiang - Journal of Translational …, 2021 - Springer
Background Accumulative evidence shows that an organoid is a more practical and reliable
tool in cancer biology research. This study aimed to identify and validate crucial genes …