Cancer, a major public health problem, is one of the world's top leading causes of death.
Common treatments for cancer include cytotoxic chemotherapy, surgery, targeted drugs …

Bile acid transporters (BATs) are integral membrane proteins belonging to various families,
such as solute carriers, organic anion transporters, and ATP-binding cassette families …

Simple Summary Clear cell renal cell carcinoma (ccRCC) is characterized by a high rate of
cell proliferation and an extensive accumulation of lipids. Uncontrolled cell growth usually …

ABCC1 and ABCC4 utilize energy from ATP hydrolysis to transport many different
molecules, including drugs, out of the cell and, as such, have been implicated in causing …

The treatment of relapse or refractory multiple myeloma (RRMM) is still a big challenge in
clinic. Recently, several clinical trials indicated that the XPO1 inhibitor, selinexor could …

ADPKD is the most common genetic renal disease, characterized by the presence of
multiple cysts which, through slow and gradual growth, lead to glomerular filtration rate …

Background Clear cell renal cell carcinoma (ccRCC) is a form of kidney cancer
characterized by dysregulated angiogenesis and multidrug resistance. Hypoxia-induced …

Background Cyclic nucleotides are critical mediators of cellular signalling in glioblastoma.
However, the clinical relevance and mechanisms of regulating cyclic nucleotides in …

Bursaphelenchus xylophilus (Pinewood nematode, PWN) is the causative agent of pine wilt
disease (PWD) which caused serious threat to pine forests in the world, especially in East …

Results: 12 coding genes and one miRNA were finally identified as prognostic biomarkers.
All of them were related to a poor prognosis. Lower expression levels of the coding genes …