Infection microenvironment-related antibacterial nanotherapeutic strategies

Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

“Nanoantibiotics”: a new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era

AJ Huh, YJ Kwon - Journal of controlled release, 2011 - Elsevier
Despite the fact that we live in an era of advanced and innovative technologies for
elucidating underlying mechanisms of diseases and molecularly designing new drugs …

Development of nanoparticles for antimicrobial drug delivery

L Zhang, D Pornpattananangkul… - Current medicinal …, 2010 - ingentaconnect.com
This review focuses on the development of nanoparticle systems for antimicrobial drug
delivery. Numerous antimicrobial drugs have been prescribed to kill or inhibit the growth of …

[HTML][HTML] Nanoparticles: Emerging carriers for drug delivery

SR Mudshinge, AB Deore, S Patil… - Saudi pharmaceutical …, 2011 - Elsevier
The core objective of nanoparticles is to control and manipulate biomacromolecular
constructs and supramolecular assemblies that are critical to living cells in order to improve …

[HTML][HTML] Nanoparticles-based therapeutics for the management of bacterial infections: a special emphasis on FDA approved products and clinical trials

F Aflakian, F Mirzavi, HT Aiyelabegan… - European Journal of …, 2023 - Elsevier
Microbial resistance has increased in recent decades as a result of the extensive and
indiscriminate use of antibiotics. The World Health Organization listed antimicrobial …

[HTML][HTML] Microbial resistance to nanotechnologies: An important but understudied consideration using antimicrobial nanotechnologies in orthopaedic implants

Z Wu, B Chan, J Low, JJH Chu, HWD Hey, A Tay - Bioactive Materials, 2022 - Elsevier
Microbial resistance to current antibiotics therapies is a major cause of implant failure and
adverse clinical outcomes in orthopaedic surgery. Recent developments in advanced …

Nanomaterials: the new antimicrobial magic bullet

J Ndayishimiye, T Kumeria, A Popat… - ACS Infectious …, 2022 - ACS Publications
Bacterial infections are a significant cause of mortality and morbidity worldwide, despite
decades of use of numerous existing antibiotics and constant efforts by researchers to …

Lipase-sensitive polymeric triple-layered nanogel for “on-demand” drug delivery

MH Xiong, Y Bao, XZ Yang, YC Wang… - Journal of the …, 2012 - ACS Publications
We report a new strategy for differential delivery of antimicrobials to bacterial infection sites
with a lipase-sensitive polymeric triple-layered nanogel (TLN) as the drug carrier. The TLN …

Targeted delivery of antibiotics using liposomes and nanoparticles: research and applications

H Pinto-Alphandary, A Andremont… - International journal of …, 2000 - Elsevier
This review examines current technologies for increasing the bioavailability of antibiotics by
means of liposomes or nanoparticles. The main focus is on liposomes. These carriers were …

Nanotechnology and pulmonary delivery to overcome resistance in infectious diseases

F Andrade, D Rafael, M Videira, D Ferreira… - Advanced drug delivery …, 2013 - Elsevier
Used since ancient times especially for the local treatment of pulmonary diseases, lungs and
airways are a versatile target route for the administration of both local and systemic drugs …