Overview of methods for characterization and visualization of a protein–protein interaction network in a multi-omics integration context

V Robin, A Bodein, MP Scott-Boyer… - Frontiers in Molecular …, 2022 - frontiersin.org
At the heart of the cellular machinery through the regulation of cellular functions, protein–
protein interactions (PPIs) have a significant role. PPIs can be analyzed with network …

A survey of current trends in computational predictions of protein-protein interactions

Y Wang, Z You, L Li, Z Chen - Frontiers of Computer Science, 2020 - Springer
Proteomics become an important research area of interests in life science after the
completion of the human genome project. This scientific is to study the characteristics of …

Unifying structural descriptors for biological and bioinspired nanoscale complexes

M Cha, EST Emre, X Xiao, JY Kim, P Bogdan… - Nature Computational …, 2022 - nature.com
Biomimetic nanoparticles are known to serve as nanoscale adjuvants, enzyme mimics and
amyloid fibrillation inhibitors. Their further development requires better understanding of …

DeepTrio: a ternary prediction system for protein–protein interaction using mask multiple parallel convolutional neural networks

X Hu, C Feng, Y Zhou, A Harrison, M Chen - Bioinformatics, 2022 - academic.oup.com
Motivation Protein–protein interaction (PPI), as a relative property, is determined by two
binding proteins, which brings a great challenge to design an expert model with an …

ACP-MHCNN: an accurate multi-headed deep-convolutional neural network to predict anticancer peptides

S Ahmed, R Muhammod, ZH Khan, S Adilina… - Scientific reports, 2021 - nature.com
Although advancing the therapeutic alternatives for treating deadly cancers has gained
much attention globally, still the primary methods such as chemotherapy have significant …

ACP-DL: a deep learning long short-term memory model to predict anticancer peptides using high-efficiency feature representation

HC Yi, ZH You, X Zhou, L Cheng, X Li, TH Jiang… - … Therapy-Nucleic Acids, 2019 - cell.com
Cancer is a well-known killer of human beings, which has led to countless deaths and
misery. Anticancer peptides open a promising perspective for cancer treatment, and they …

A high efficient biological language model for predicting protein–protein interactions

Y Wang, ZH You, S Yang, X Li, TH Jiang, X Zhou - Cells, 2019 - mdpi.com
Many life activities and key functions in organisms are maintained by different types of
protein–protein interactions (PPIs). In order to accelerate the discovery of PPIs for different …

MLMDA: a machine learning approach to predict and validate MicroRNA–disease associations by integrating of heterogenous information sources

K Zheng, ZH You, L Wang, Y Zhou, LP Li… - Journal of translational …, 2019 - Springer
Background Emerging evidences show that microRNA (miRNA) plays an important role in
many human complex diseases. However, considering the inherent time-consuming and …

Predicting drug− disease associations via sigmoid kernel-based convolutional neural networks

HJ Jiang, ZH You, YA Huang - Journal of translational medicine, 2019 - Springer
Background In the process of drug development, computational drug repositioning is
effective and resource-saving with regards to its important functions on identifying new drug …

AutoPPI: An Ensemble of Deep Autoencoders for Protein–Protein Interaction Prediction

G Czibula, AI Albu, MI Bocicor, C Chira - Entropy, 2021 - mdpi.com
Proteins are essential molecules, that must correctly perform their roles for the good health
of living organisms. The majority of proteins operate in complexes and the way they interact …