The role of immune inflammation in aneurysmal subarachnoid hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease, which mainly
caused by the rupture of an intracranial aneurysm. Clinical trials have demonstrated that …
caused by the rupture of an intracranial aneurysm. Clinical trials have demonstrated that …
SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage
DY Xia, JL Yuan, XC Jiang, M Qi, NS Lai… - Frontiers in …, 2021 - frontiersin.org
Mounting evidence has suggested that modulating microglia polarization from pro-
inflammatory M1 phenotype to anti-inflammatory M2 state might be a potential therapeutic …
inflammatory M1 phenotype to anti-inflammatory M2 state might be a potential therapeutic …
Neuroprotective strategies in aneurysmal subarachnoid hemorrhage (aSAH)
J Weiland, A Beez, T Westermaier, E Kunze… - International journal of …, 2021 - mdpi.com
Aneurysmal subarachnoid hemorrhage (aSAH) remains a disease with high mortality and
morbidity. Since treating vasospasm has not inevitably led to an improvement in outcome …
morbidity. Since treating vasospasm has not inevitably led to an improvement in outcome …
Neutrophil extracellular traps may be a potential target for treating early brain injury in subarachnoid hemorrhage
H Zeng, X Fu, J Cai, C Sun, M Yu, Y Peng… - Translational stroke …, 2022 - Springer
Neuroinflammation is closely associated with poor prognosis in patients with subarachnoid
hemorrhage (SAH). The purpose of this study was to investigate the role of neutrophil …
hemorrhage (SAH). The purpose of this study was to investigate the role of neutrophil …
Isoliquiritigenin mitigates oxidative damage after subarachnoid hemorrhage in vivo and in vitro by regulating Nrf2-dependent Signaling Pathway via Targeting of …
JQ Liu, XT Zhao, FY Qin, JW Zhou, F Ding, G Zhou… - Phytomedicine, 2022 - Elsevier
Background Oxidative stress is a crucial factor leading to subarachnoid hemorrhage (SAH)-
induced early brain injury (EBI). Isoliquiritigenin has been verified as a powerful anti-oxidant …
induced early brain injury (EBI). Isoliquiritigenin has been verified as a powerful anti-oxidant …
Functions of resolvin D1-ALX/FPR2 receptor interaction in the hemoglobin-induced microglial inflammatory response and neuronal injury
GJ Liu, T Tao, H Wang, Y Zhou, X Gao, YY Gao… - Journal of …, 2020 - Springer
Background Early brain injury (EBI) has been thought to be a key factor affecting the
prognosis of subarachnoid hemorrhage (SAH). Many pathologies are involved in EBI, with …
prognosis of subarachnoid hemorrhage (SAH). Many pathologies are involved in EBI, with …
TRAF3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting TAK1-dependent MAPKs and NF-κB pathways
Y Zhou, T Tao, G Liu, X Gao, Y Gao, Z Zhuang… - Cell Death & …, 2021 - nature.com
Neuronal apoptosis has an important role in early brain injury (EBI) following subarachnoid
hemorrhage (SAH). TRAF3 was reported as a promising therapeutic target for stroke …
hemorrhage (SAH). TRAF3 was reported as a promising therapeutic target for stroke …
Luteolin Confers Cerebroprotection after Subarachnoid Hemorrhage by Suppression of NLPR3 Inflammasome Activation through Nrf2‐Dependent Pathway
ZH Zhang, JQ Liu, CD Hu, XT Zhao… - Oxidative Medicine …, 2021 - Wiley Online Library
Luteolin (LUT) possesses multiple biologic functions and has beneficial effects for
cardiovascular and cerebral vascular diseases. Here, we investigated the protective effects …
cardiovascular and cerebral vascular diseases. Here, we investigated the protective effects …
PDK4 Decrease Neuronal Apoptosis via Inhibiting ROS-ASK1/P38 Pathway in Early Brain Injury After Subarachnoid Hemorrhage
X Gao, YY Gao, HY Yan, GJ Liu, Y Zhou… - Antioxidants & Redox …, 2022 - liebertpub.com
Aims: Metabolic disorders may play key roles in oxidative stress and neuronal apoptosis in
response to early brain injury (EBI) after subarachnoid hemorrhage (SAH). Pyruvate …
response to early brain injury (EBI) after subarachnoid hemorrhage (SAH). Pyruvate …
Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid …
D Xia, J Yuan, D Wu, H Dai, Z Zhuang - Frontiers in Immunology, 2023 - frontiersin.org
The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain
containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a …
containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a …