Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease

J Zhou, L Chan, S Zhou - Current medicinal chemistry, 2012 - ingentaconnect.com
There is evidence that Trigonella foenum-graecum L.(fenugreek), a traditional Chinese herb,
and its components are beneficial in the prevention and treatment of diabetes and central …

Pharmacological effects of Trigonella foenum-graecum L. in health and disease

UCS Yadav, NZ Baquer - Pharmaceutical biology, 2014 - Taylor & Francis
Context: The health benefits and medicinal properties of herbal food products are known
since antiquity. Fenugreek [Trigonella foenum-graecum Linn.(Fabaceae)], a seed spice …

Mechanisms and significance of cell volume regulation

F Lang - Journal of the American college of nutrition, 2007 - Taylor & Francis
Survival of human and animal cells requires avoidance of excessive alterations of cell
volume. The osmolarity amassed by cellular accumulation of organic substances must be …

Diosgenin, a Steroid Saponin of Trigonella foenum graecum (Fenugreek), Inhibits Azoxymethane-Induced Aberrant Crypt Foci Formation in F344 Rats and Induces …

J Raju, JMR Patlolla, MV Swamy, CV Rao - Cancer Epidemiology Biomarkers …, 2004 - AACR
Trigonella foenum graecum (fenugreek) is traditionally used to treat disorders such as
diabetes, high cholesterol, wounds, inflammation, and gastrointestinal ailments. Recent …

The role of diosgenin in diabetes and diabetic complications

Q Gan, J Wang, J Hu, G Lou, H Xiong, C Peng… - The Journal of steroid …, 2020 - Elsevier
Diabetes mellitus is a chronic and common metabolic disease that seriously endangers
human health. Hyperglycemia and long-term metabolic disorders in diabetes will cause …

Therapeutic potential of diosgenin and its major derivatives against neurological diseases: recent advances

B Cai, Y Zhang, Z Wang, D Xu, Y Jia… - Oxidative medicine …, 2020 - Wiley Online Library
Diosgenin (DG), a well‐known steroidal sapogenin, is present abundantly in medicinal
herbs such as Dioscorea rhizome, Dioscorea villosa, Trigonella foenum-graecum, Smilax …

A review of Algerian medicinal plants used in the treatment of diabetes

N Hamza, B Berke, A Umar, C Cheze, H Gin… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Plants are traditionally used in Algeria to treat many
disorders, including diabetes mellitus. Knowledge of the plants that are used may provide …

Metabolic and molecular action of Trigonella foenum-graecum (fenugreek) and trace metals in experimental diabetic tissues

NZ Baquer, P Kumar, A Taha, RK Kale, SM Cowsik… - Journal of …, 2011 - Springer
Diabetes mellitus is a heterogeneous metabolic disorder characterized by hyperglycaemia
resulting in defective insulin secretion, resistance to insulin action or both. The use of …

Anticancer activity of diosgenin and its molecular mechanism

Q Ren, Q Wang, X Zhang, M Wang, H Hu… - Chinese journal of …, 2023 - Springer
Diosgenin, a steroidal sapogenin, obtained from Trigonella foenum-graecum, Dioscorea,
and Rhizoma polgonati, has shown high potential and interest in the treatment of various …

Effect of fenugreek (Trigonella foenum-graecum L) seeds on serum parameters in normal and streptozotocin-induced diabetic rats

A Eidi, M Eidi, M Sokhteh - Nutrition research, 2007 - Elsevier
Many herbal medicines have been recommended for the treatment of diabetes. The
antidiabetic effect of fenugreek ethanolic extract (Trigonella-foenum graecum L) was …