The human pathogenic trypanosomatid species collectively called the “TriTryp parasites”–
Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp.–have complex life cycles …

Glycolysis and glyconeogenesis play crucial roles in the ATP supply and synthesis of
glycoconjugates, important for the viability and virulence, respectively, of the human …

Protozoan parasites of genus Leishmania are the causative agents of leishmaniasis. These
digenetic microorganisms undergo a marked environmental temperature shift (TS) during …

Inorganic polyphosphate (polyP) is a polymer of three to hundreds of phosphate units bound
by high‐energy phosphoanhydride bonds and present from bacteria to humans. Most polyP …

Background Haemaphysalis longicornis is an obligate hematophagous ectoparasite, which
transmits various pathogens to humans, livestock and wild animals. Hexokinase (HK) is a …

Glycosomes are peroxisome-related organelles that have been identified in kinetoplastids
and diplonemids. The hallmark of glycosomes is their harboring of the majority of the …

Significance: Hexokinases are key enzymes that are responsible for the first reaction of
glycolysis, but they also moonlight other cellular processes, including mitochondrial redox …

Glycosomes are peroxisome-related organelles found in all kinetoplastid protists, including
the human pathogenic species of the family Trypanosomatidae: Trypanosoma brucei …

Background Glycosomes are a specialized form of peroxisomes (microbodies) present in
unicellular eukaryotes that belong to the Kinetoplastea order, such as Trypanosoma and …

Glucokinase genes, found in the genome databases of Trypanosoma cruzi and Leishmania
major, were cloned and sequenced. Their expression in Escherichia coli resulted in the …