Arsenic, a metalloid and naturally occurring element, is one of the most abundant elements
in the earth's crust. Water is contaminated by arsenic through natural sources (underground …

Chronic kidney disease (CKD) is a common progressive disease that is typically
characterized by the permanent loss of functional nephrons. As injured nephrons become …

Arsenic is a non-essential, environmentally ubiquitous toxic metalloid. In response to this
pervasive environmental challenge, organisms evolved mechanisms to confer resistance to …

Heavy metals in drinking water can threat human health and may induce several diseases.
The association between heavy metals exposure and chronic kidney disease (CKD) has …

Natural contamination of drinking water with arsenic results in the exposure of millions of
people world-wide to unacceptable levels of this metalloid. This is a serious global health …

Humans are ubiquitously exposed to arsenic from multiple sources, and chronic arsenic
exposure may be associated with male reproductive health. Although association regarding …

Arsenic (As) contamination in water or food is a global issue affecting hundreds of millions of
people. Although As is classified as a group 1 carcinogen and is associated with multiple …

Arsenic-induced carcinogenesis is a worldwide health problem. Identifying the molecular
mechanisms responsible for the induction of arsenic-induced cancers is important for …

Broad inter-individual variation exists in susceptibility to arsenic-induced tumours, likely
involving differences in the ability of individuals to eliminate this metalloid. We recently …

MRP4 is an ABC membrane transporter involved in clinical outcomes as it is located in many
tissues that manages the transport and the elimination of many drugs. This review explores …