Role of main RNA methylation in hepatocellular carcinoma: N6-methyladenosine, 5-methylcytosine, and N1-methyladenosine
Y Xu, M Zhang, Q Zhang, X Yu, Z Sun, Y He… - Frontiers in cell and …, 2021 - frontiersin.org
RNA methylation is considered a significant epigenetic modification, a process that does not
alter gene sequence but may play a necessary role in multiple biological processes, such as …
alter gene sequence but may play a necessary role in multiple biological processes, such as …
Structural Mapping of the Base Stacks Containing Post-transcriptionally Modified Bases in RNA
Post-transcriptionally modified bases play vital roles in many biochemical processes
involving RNA. Analysis of the non-covalent interactions associated with these bases in …
involving RNA. Analysis of the non-covalent interactions associated with these bases in …
Exploring the Impact of mRNA Modifications on Translation Efficiency and Immune Tolerance to Self-Antigens
M Sioud, A Juzeniene, S Sæbøe-Larssen - Vaccines, 2024 - mdpi.com
Therapeutic modified mRNAs are being developed for a broad range of human diseases.
However, the impact of potential miscoding of modified mRNAs on self-tolerance remains …
However, the impact of potential miscoding of modified mRNAs on self-tolerance remains …
Molecular Dynamics Simulations of the Aptamer Domain of Guanidinium Ion Binding Riboswitch ykkC-III: Structural Insights into the Discrimination of Cognate and …
I Negi, AS Mahmi, P Seelam Prabhakar… - Journal of Chemical …, 2021 - ACS Publications
Guanidinium ion is a toxic cellular metabolite. The ykkC-III riboswitch, an mRNA stretch,
regulates the gene expression by undergoing a conformational change in response to the …
regulates the gene expression by undergoing a conformational change in response to the …
An Atlas of the base inter-RNA stacks involved in bacterial translation
Nucleobase-specific noncovalent interactions play a crucial role in translation. Herein, we
provide a comprehensive analysis of the stacks between different RNA components in the …
provide a comprehensive analysis of the stacks between different RNA components in the …
Structural Properties of Hachimoji Nucleic Acids and Their Building Blocks: Comparison of Genetic Systems with Four, Six and Eight Alphabets
Expansion of the genetic alphabet is an ambitious goal. A recent breakthrough has led to the
eight‐base (hachimoji) genetics having canonical and unnatural bases. However, very little …
eight‐base (hachimoji) genetics having canonical and unnatural bases. However, very little …