Atherosclerosis, the underlying cause of cardiovascular disease (CVD), is a worldwide
cause of morbidity and mortality. Reducing ApoB-containing lipoproteins—chiefly, LDL (low …

Cardiovascular diseases (CVDs), specifically lipid-driven atherosclerotic CVDs, remain the
number one cause of death worldwide. The lectin-like oxidized low-density lipoprotein (LDL) …

Altered production of reactive oxygen species (ROS), causing lipid peroxidation and DNA
damage, contributes to the progression of atherosclerosis and cancer. Lectin-like oxidized …

The mannose receptor is a member of the C-type lectin (CLEC) family, which can bind and
internalize a variety of endogenous and pathogen-associated ligands. Because of these …

Eukaryotic cells employ distinct means to release specific signals and material. Research
within the last decade has identified different types of membrane-enclosed structures …

Cardiovascular diseases are the leading cause of death worldwide. Approximately 85% of
all deaths from cardiovascular disease are due to acute myocardial infarction (AMI) and …

The lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is the major receptor for
binding and uptake of oxidized low-density lipoprotein (oxLDL) in endothelial cells. LOX-1 is …

Exosomes, as potent intercellular communication tools, have garnered significant attention
due to their unique cargo-carrying capabilities, which enable them to influence diverse …

Atherosclerosis is the leading cause of death in developed countries. The pathogenetic
mechanism relies on a macrophage-based immune reaction to low density lipoprotein (LDL) …

Atherosclerosis (AS) is a chronic inflammatory vascular disease. Dysregulated lipid
metabolism, oxidative stress, and inflammation are the major mechanisms implicated in the …