The importance of a fully functioning placenta for a good pregnancy outcome is
unquestioned. Loss of function can lead to pregnancy complications and is often detected by …

Human pregnancy depends on the proper development of the embryo prior to implantation
and the implantation of the embryo into the uterine wall. During the pre-implantation phase …

Homeostatic regulation of the maternal milieu during pregnancy is critical for maternal and
fetal health. The placenta facilitates critical communication between maternal and fetal …

The intracellular journey of extracellular vesicles (EVs) cannot be ignored in various
biological pathological processes. In this review, the biogenesis, biological functions, uptake …

Mammalian cardiomyocytes undergo major maturational changes in preparation for birth
and postnatal life. Immature cardiomyocytes contribute to cardiac growth via proliferation …

During pregnancy, there is an intense crosstalk between mother and placenta. During the
entire time of pregnancy, the maternal system deals with a huge amount of foreign (fetal) …

Abstract Endometriosis, affecting 10% of women, is defined as implantation, survival, and
growth of endometrium-like/endometriotic tissue outside the uterine cavity, causing …

Placental extracellular vesicles (EVs) have increasingly been recognized as a major
mediator of feto-maternal communication. However, the cellular and molecular mechanisms …

Background The nano-sized, lipid bilayer-delimited placental extracellular vesicles (PEVs)
released by the placenta are now regarded as important mediators involved in various …

The placenta controls the growth of the fetus and ensures its immune protection. Key to
these functions, the syncytiotrophoblast (SYN) is a syncytium formed by fusion of underlying …