P450 BM3 (CYP102A1): connecting the dots
CJC Whitehouse, SG Bell, LL Wong - Chemical Society Reviews, 2012 - pubs.rsc.org
P450BM3 (CYP102A1), a fatty acid hydroxylase from Bacillus megaterium, has been
extensively studied over a period of almost forty years. The enzyme has been redesigned to …
extensively studied over a period of almost forty years. The enzyme has been redesigned to …
Intracellular transformation rates of fatty acids are influenced by expression of the fatty acid transporter FadL in Escherichia coli cell membrane
Fatty acids have a low permeability through the cell membrane. Therefore, the intracellular
biotransformation of fatty acids can be slow due to supply limitations. The effects of …
biotransformation of fatty acids can be slow due to supply limitations. The effects of …
Bioprocess engineering to produce 10-hydroxystearic acid from oleic acid by recombinant Escherichia coli expressing the oleate hydratase gene of …
EY Jeon, JH Lee, KM Yang, YC Joo, DK Oh… - Process Biochemistry, 2012 - Elsevier
Microbial hydroxylation of long chain fatty acids has been extensively investigated.
However, biotransformation productivity remains below ca. 1.0 g/g cell dry weight (CDW)/h …
However, biotransformation productivity remains below ca. 1.0 g/g cell dry weight (CDW)/h …
Endocytosing Escherichia coli as a Whole-Cell Biocatalyst of Fatty Acids
Whole cell biocatalysts can be used to convert fatty acids into various value-added products.
However, fatty acid transport across cellular membranes into the cytosol of microbial cells …
However, fatty acid transport across cellular membranes into the cytosol of microbial cells …
[HTML][HTML] Engineering caveolin-mediated endocytosis in Saccharomyces cerevisiae
As a potential substitute for fatty acids, common low-cost oils could be used to produce
acetyl-CoA derivatives, which meet the needs of low-cost industrial production. However …
acetyl-CoA derivatives, which meet the needs of low-cost industrial production. However …
Ethambutol-mediated cell wall modification in recombinant Corynebacterium glutamicum increases the biotransformation rates of cyclohexanone derivatives
JY Yun, JE Lee, KM Yang, S Cho, A Kim… - Bioprocess and …, 2012 - Springer
The effects of structural modification of cell wall on the biotransformation capability by
recombinant Corynebacterium glutamicum cells, expressing the chnB gene encoding …
recombinant Corynebacterium glutamicum cells, expressing the chnB gene encoding …
Rational design and directed evolution of CYP102A1 (BM3) for regio-specific hydroxylation of isoflavone
S Ko, YH Yang, KY Choi, BG Kim - Biotechnology and Bioprocess …, 2015 - Springer
Isoflavonoids are a class of polycyclic aromatic hydrocarbon compounds originating from
plants as secondary metabolites. Their oxidative metabolites such as ortho …
plants as secondary metabolites. Their oxidative metabolites such as ortho …
Cloning, expression, and characterization of P450 monooxygenase CYP102H1 from Nocardia farcinica
YH Chung, JW Song, KY Choi, JW Yoon… - Journal of the Korean …, 2012 - Springer
To isolate a new P450 monooxygenase belonging to the CYP102 family, CYP102H1 of
Nocardia farcinica IFM 10152 (ie, pnf11580) was cloned, expressed, and partially …
Nocardia farcinica IFM 10152 (ie, pnf11580) was cloned, expressed, and partially …
Improving the catalytic activity of cyclohexanone monooxygenase-based whole-cell biocatalysts under substrate toxic conditions
SM Lee, JY Yun, J Woo, SH Kang, KM Yang… - Journal of the Korean …, 2011 - Springer
The catalytic activity of oxygenase-based whole-cell biocatalysts is heavily influenced by
substrate and product toxicities due to cell membrane permeabilization and protein …
substrate and product toxicities due to cell membrane permeabilization and protein …