The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

The phenomenon of antibiotic resistance (AR) and its increasing global trends and
destructive waves concerns patients and the healthcare system. In order to combat AR, it is …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has demonstrated a clear
need for high-throughput, multiplexed and sensitive assays for detecting severe acute …

Many CRISPR-Cas immune systems generate guide (g) RNAs using trans-activating
CRISPR RNAs (tracrRNAs). Recent work revealed that Cas9 tracrRNAs could be …

The integration of nucleic acid amplification (NAA) with the CRISPR detection system has
led to significant advancements and opportunities for development in molecular diagnostics …

The COVID-19 pandemic (caused by the SARS_CoV_2 virus) has emphasized the need for
quick, easy-to-operate, reliable, and affordable diagnostic tests and devices at the Point-of …

Growing studies focusing on nuclear acid detection via the emerging CRISPR technique
demonstrate its promising application. However, limited works solve the identification of non …

The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-
related proteins (CRISPR/Cas) are regarded as the next generation of molecular diagnostic …

Reviewed are nucleic acid detection assays that incorporate clustered regularly interspaced
short palindromic repeats (CRISPR)-based diagnostics and microfluidic devices and …

Detection of microbial cell-free DNA (cfDNA) circulating in the bloodstream has emerged as
a promising new approach for diagnosing infection. Microbial diagnostics based on cfDNA …