The potential of DNA methylation as a biomarker for obesity and smoking
A Heikkinen, S Bollepalli… - Journal of internal …, 2022 - Wiley Online Library
DNA methylation is an epigenetic modification that has consistently been shown to be linked
with a variety of human traits and diseases. Because DNA methylation is dynamic and …
with a variety of human traits and diseases. Because DNA methylation is dynamic and …
Lipid phenotypes and DNA methylation: a review of the literature
Abstract Purpose of Review Epigenetic modifications via DNA methylation have previously
been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this …
been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this …
[HTML][HTML] Carbohydrate and fat intake associated with risk of metabolic diseases through epigenetics of CPT1A
CQ Lai, LD Parnell, CE Smith, T Guo… - The American journal of …, 2020 - Elsevier
Background Epigenome-wide association studies identified the cg00574958 DNA
methylation site at the carnitine palmitoyltransferase-1A (CPT1A) gene to be associated with …
methylation site at the carnitine palmitoyltransferase-1A (CPT1A) gene to be associated with …
DNA methylation near CPT1A and changes in triglyceride-rich lipoproteins in response to weight-loss diet interventions
Context Carnitine palmitoyltransferase-1A, encoded by the CPT1A gene, plays a key role in
the oxidation of long-chain fatty acids in the mitochondria and may be important in …
the oxidation of long-chain fatty acids in the mitochondria and may be important in …
Use of human PBMC to analyse the impact of obesity on lipid metabolism and metabolic status: a proof-of-concept pilot study
Peripheral blood mononuclear cells (PBMC) are widely used as a biomarker source in
nutrition/obesity studies because they reflect gene expression profiles of internal tissues. In …
nutrition/obesity studies because they reflect gene expression profiles of internal tissues. In …
Effects of Breastfeeding and Formula Feeding on the Expression Level of FTO, CPT1A and PPAR-α Genes in Healthy Infants
Purpose The study aimed to investigate the effect of breastfeeding, formula feeding and mix
feeding (breastfed plus formula-fed) on the expression level of obesity-predisposing genes …
feeding (breastfed plus formula-fed) on the expression level of obesity-predisposing genes …
Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis
Background/objectives Obesity, defined as excessive fat accumulation that represents a
health risk, is increasing in adults and children, reaching global epidemic proportions. Body …
health risk, is increasing in adults and children, reaching global epidemic proportions. Body …
Peripheral blood cells, a transcriptomic tool in nutrigenomic and obesity studies: current state of the art
Gene expression profile of peripheral blood cells (PBC) is able to reflect useful aspects of
the whole body metabolic status. Therefore, and favored by the huge development of “omic” …
the whole body metabolic status. Therefore, and favored by the huge development of “omic” …
Mitochondrial reprogramming in peripheral blood mononuclear cells of patients with glycogen storage disease type Ia
A Rossi, A Assunto, C Rosano, S Tucci, M Ruoppolo… - Genes & nutrition, 2023 - Springer
Background Glycogen storage disease type Ia (GSDIa) is an inborn metabolic disorder
caused by the deficiency of glucose-6-phospatase-α (G6Pase-α) leading to mitochondrial …
caused by the deficiency of glucose-6-phospatase-α (G6Pase-α) leading to mitochondrial …
Long non-coding RNA LY86-AS1 and HCG27_201 expression in type 2 diabetes mellitus
Abstract Long non-coding RNAs (LncRNAs) are non-coding RNAs. The potential roles of
lncRNAs in type 2 diabetes mellitus (T2DM) are not well-known. In this study, we aim to …
lncRNAs in type 2 diabetes mellitus (T2DM) are not well-known. In this study, we aim to …