Abstract Phosphoglycerate kinase 1 (PGK1) is an essential enzyme in the aerobic glycolysis
pathway. PGK1 catalyzes the reversible transfer of a phosphate group from 1, 3 …

Abstract Phosphoglycerate kinase 1 (PGK1) is the first critical enzyme to produce ATP in the
glycolytic pathway. PGK1 is not only a metabolic enzyme but also a protein kinase, which …

Metabolic reprogramming is a common hallmark of cancers and involves alterations in many
metabolic pathways during tumor initiation and progression. However, the cancer-specific …

Background: Exosomes are nanoscale membrane vesicles secreted by both normal and
cancer cells, and cancer cell-derived exosomes play an important role in the cross-talk …

Understanding the molecular interaction between ligand and receptor is important for
providing the basis for the development of regenerative drugs. Although it has been reported …

Apoptosis and autophagy are the two prominent forms of developmental cell death, and
researches have shown that crosstalk exists between these two processes. A prior study …

Abstract Phosphoglycerate kinase 1 (PGK1) is an essential enzyme that catalyzes
adenosine 5′-triphosphate (ATP) production in aerobic glycolysis. In addition to regulating …

Cancer is usually a result of abnormal glucose uptake and imbalanced nutrient
metabolization. The dysregulation of glucose metabolism, which controls the processes of …

Abstract Phosphoglycerate kinase 1 (PGK1) is the first enzyme in glycolysis to generate a
molecule of ATP in the conversion of 1, 3-bisphosphoglycerate (1, 3-BPG) to 3 …

Background Endometrial carcinoma represents one of the most common cancer types of the
female reproductive tract. If diagnosed at an early stage, the 5-year survival rate is …