Nanotechnology as a tool to advance research and treatment of non-oncologic urogenital diseases

J Loloi, M Babar, KP Davies… - … Advances in Urology, 2022 - journals.sagepub.com
Nanotechnology represents an expanding area of research and innovation in almost every
field of science, including Medicine, where nanomaterial-based products have been …

A high salt diet impairs the bladder epithelial barrier and activates the NLRP3 and NF‑κB signaling pathways to induce an overactive bladder in vivo

J Xue, Z Zhou, Z Zhu, Q Sun… - Experimental and …, 2024 - spandidos-publications.com
Overactive bladder (OAB) is a condition characterized by an urgency to urinate, which is
associated with the urodynamic observation of detrusor overexcitation. Although the etiology …

Enuresis and overactive bladder in sickle cell patients: a narrative review of the literature

O Gaye, M Seck, NM Thiam, A Ndong, PA Fall - World Journal of Urology, 2023 - Springer
Objective The aim of this review is to clarify the prevalence, pathophysiology and clinical
presentation of enuresis and overactive bladder in sickle cell patients. Materials and …

Impact of intravascular hemolysis on functional and molecular alterations in the urinary bladder: implications for an overactive bladder in sickle cell disease

THR Silveira, DA Pereira, DA Pereira… - Frontiers in …, 2024 - frontiersin.org
Patients with sickle cell disease (SCD) display an overactive bladder (OAB). Intravascular
hemolysis in SCD is associated with various severe SCD complications. However, no …

Dysregulated NO/PDE5 signaling in the sickle cell mouse lower urinary tract: reversal by oral nitrate therapy

B Musicki, UA Anele, JD Campbell, S Karakus, S Shiva… - Life sciences, 2019 - Elsevier
Aims Nitric oxide (NO) has a critical, but not well understood, influence in the physiology of
the lower urinary tract. We evaluated the effect of NO/phosphodiesterase (PDE) 5 signaling …

[PDF][PDF] IMPACTO DA HEMÓLISE INTRAVASCULAR NAS ALTERAÇÕES FUNCIONAIS E MOLECULARES NA BEXIGA URINÁRIA: IMPLICAÇÃO PARA A BEXIGA …

THRE SILVEIRA - usf.edu.br
Pacientes com anemia falciforme (AF) apresentam hemólise intravascular, resultando em
níveis elevados de hemoglobina plasmática. A hemoglobina em excesso reage com o óxido …

[引用][C] NO-releasing nanoparticles ameliorate detrusor overactivity in transgenic sickle cell mice via restored NO/ROCK signaling

S Karakus, B Musicki, MS Navati, JM Friedman… - … of Pharmacology and …, 2020 - ASPET