Retrospective and prospective perspectives on zoonotic brucellosis

E Moreno - Frontiers in microbiology, 2014 - frontiersin.org
Members of the genus Brucella are pathogenic bacteria exceedingly well adapted to their
hosts. The bacterium is transmitted by direct contact within the same host species or …

An evolutionary strategy for a stealthy intracellular Brucella pathogen

A Martirosyan, E Moreno, JP Gorvel - Immunological reviews, 2011 - Wiley Online Library
Brucella is an intracellular bacterial pathogen that causes abortion and infertility in mammals
and leads to a debilitating febrile illness that can progress into a long lasting disease with …

If You're Not Confused, You're Not Paying Attention: Ochrobactrum Is Not Brucella

E Moreno, EA Middlebrook… - Journal of clinical …, 2023 - Am Soc Microbiol
Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a
severe animal and human disease. Recently, a group of taxonomists merged the brucellae …

What have we learned from brucellosis in the mouse model?

MJ Grilló, JM Blasco, JP Gorvel, I Moriyón, E Moreno - Veterinary research, 2012 - Springer
Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts
is often precluded by practical, economical and ethical reasons and mice are widely used …

Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host

RM Roop, JM Gaines, ES Anderson… - Medical microbiology …, 2009 - Springer
Brucella strains produce abortion and infertility in their natural hosts and a zoonotic disease
in humans known as undulant fever. These bacteria do not produce classical virulence …

Pathogenicity and Its Implications in Taxonomy: The Brucella and Ochrobactrum Case

E Moreno, JM Blasco, JJ Letesson, JP Gorvel… - Pathogens, 2022 - mdpi.com
The intracellular pathogens of the genus Brucella are phylogenetically close to
Ochrobactrum, a diverse group of free-living bacteria with a few species occasionally …

The one hundred year journey of the genus Brucella (Meyer and Shaw 1920)

E Moreno - FEMS Microbiology Reviews, 2021 - academic.oup.com
The genus Brucella, described by Meyer and Shaw in 1920, comprises bacterial pathogens
of veterinary and public health relevance. For 36 years, the genus came to include three …

Brucella Genomics: Macro and Micro Evolution

M Suárez-Esquivel, E Chaves-Olarte, E Moreno… - International journal of …, 2020 - mdpi.com
Brucella organisms are responsible for one of the most widespread bacterial zoonoses,
named brucellosis. The disease affects several species of animals, including humans. One …

The Lipopolysaccharide Core of Brucella abortus Acts as a Shield Against Innate Immunity Recognition

R Conde-Alvarez, V Arce-Gorvel, M Iriarte… - PLoS …, 2012 - journals.plos.org
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular
patterns to launch inflammatory responses leading to the activation of adaptive immunity …

Induction of TLR4/TLR2 interaction and heterodimer formation by low endotoxic atypical LPS

S Francisco, JM Billod, J Merino, C Punzón… - Frontiers in …, 2022 - frontiersin.org
The Toll-like receptor 4 (TLR4)/myeloid differentiation protein-2 (MD-2) complex is
considered the major receptor of the innate immune system to recognize …