The absolute reliance of the mammalian brain on oxygen to generate ATP renders it acutely
vulnerable to hypoxia, whether at high altitude or in clinical settings of anemia or pulmonary …

Globally, about 400 million people reside at terrestrial altitudes above 1500 m, and more
than 100 million lowlanders visit mountainous areas above 2500 m annually. The …

Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …

High altitudes are physiologically challenging: the hypobaric hypoxia, cold, and increased
ultraviolet radiation mean humans ascending to high altitude faster than they acclimatize risk …

The low atmospheric pressure and low oxygen content in high-altitude environment have
great impacts on the functions of human body. Especially for the personnel engaged in …

Abstract Changes in cerebral blood flow (CBF) may occur with acute exposure to high
altitude; however, the CBF of the brain parenchyma has not been studied to date. In this …

Introduction The sharpened Romberg test (SRT) is a physical maneuver that has been used
to identify ataxia in individuals in resource-limited settings. Previous research has suggested …

Atherosclerotic disease has been associated with increased risk of severe neurovascular
consequences including transient ischemic attacks, ischemic strokes, and even mortality …

Background: In human beings exposed to high altitude, cerebral magnetic resonance
imaging (cMRI) revealed alterations ranging from subclinical cerebral edema formation to …

Purpose Orthostasis at sea level decreases brain tissue oxygenation and increases risk of
syncope. High altitude reduces brain and peripheral muscle tissue oxygenation. This study …