Predicting RNA structures and functions by artificial intelligence
RNA functions by interacting with its intended targets structurally. However, due to the
dynamic nature of RNA molecules, RNA structures are difficult to determine experimentally …
dynamic nature of RNA molecules, RNA structures are difficult to determine experimentally …
A comprehensive survey of foundation models in medicine
Foundation models (FMs) are large-scale deeplearning models that are developed using
large datasets and self-supervised learning methods. These models serve as a base for …
large datasets and self-supervised learning methods. These models serve as a base for …
RNA-TorsionBERT: leveraging language models for RNA 3D torsion angles prediction
Motivation Predicting the 3D structure of RNA is an ongoing challenge that has yet to be
completely addressed despite continuous advancements. RNA 3D structures rely on …
completely addressed despite continuous advancements. RNA 3D structures rely on …
PharmaGPT: Domain-Specific Large Language Models for Bio-Pharmaceutical and Chemistry
Large language models (LLMs) have revolutionized Natural Language Processing (NLP) by
minimizing the need for complex feature engineering. However, the application of LLMs in …
minimizing the need for complex feature engineering. However, the application of LLMs in …
Advances in the field of RNA 3D structure prediction and modeling, with purely theoretical approaches, and with the use of experimental data
Recent advancements in RNA three-dimensional (3D) structure prediction have provided
significant insights into RNA biology, highlighting the essential role of RNA in cellular …
significant insights into RNA biology, highlighting the essential role of RNA in cellular …
Foundation model for advancing healthcare: Challenges, opportunities, and future directions
Foundation model, which is pre-trained on broad data and is able to adapt to a wide range
of tasks, is advancing healthcare. It promotes the development of healthcare artificial …
of tasks, is advancing healthcare. It promotes the development of healthcare artificial …
Foundation models for bioinformatics
Z Chen, L Wei, G Gao - Quantitative Biology, 2024 - Wiley Online Library
Transformer‐based foundation models such as ChatGPTs have revolutionized our daily life
and affected many fields including bioinformatics. In this perspective, we first discuss about …
and affected many fields including bioinformatics. In this perspective, we first discuss about …
Rinalmo: General-purpose rna language models can generalize well on structure prediction tasks
Ribonucleic acid (RNA) plays a variety of crucial roles in fundamental biological processes.
Recently, RNA has become an interesting drug target, emphasizing the need to improve our …
Recently, RNA has become an interesting drug target, emphasizing the need to improve our …
Comprehensive benchmarking of large language models for RNA secondary structure prediction
Inspired by the success of large language models (LLM) for DNA and proteins, several LLM
for RNA have been developed recently. RNA-LLM uses large datasets of RNA sequences to …
for RNA have been developed recently. RNA-LLM uses large datasets of RNA sequences to …
GenerRNA: A generative pre-trained language model for de novo RNA design
The design of RNA plays a crucial role in developing RNA vaccines, nucleic acid
therapeutics, and innovative biotechnological tools. However, existing techniques frequently …
therapeutics, and innovative biotechnological tools. However, existing techniques frequently …