In Vitro Bone Cell Models: Impact of Fluid Shear Stress on Bone Formation

C Wittkowske, GC Reilly, D Lacroix… - … in bioengineering and …, 2016 - frontiersin.org
This review describes the role of bone cells and their surrounding matrix in maintaining
bone strength through the process of bone remodeling. Subsequently, this work focusses on …

In vitro collagen biomarkers in mechanically stimulated human tendon cells: a systematic review

K Squier, R Mousavizadeh, F Damji… - Connective Tissue …, 2024 - Taylor & Francis
Objective The aim of this study was to comprehensively examine and summarize the
available in vitro evidence regarding the relationship between mechanical stimulation and …

Fluid shear stress impacts ovarian cancer cell viability, subcellular organization, and promotes genomic instability

AR Hyler, NC Baudoin, MS Brown, MA Stremler… - PloS one, 2018 - journals.plos.org
Ovarian cancer cells are exposed to physical stress in the peritoneal cavity during both
tumor growth and dissemination. Ascites build-up in metastatic ovarian cancer further …

Dielectric elastomer actuator for mechanical loading of 2D cell cultures

A Poulin, CS Demir, S Rosset, TV Petrova, H Shea - Lab on a Chip, 2016 - pubs.rsc.org
We demonstrate the use of dielectric elastomer actuators (DEAs) for mechanical stimulation
of cells in vitro. The development of living tissues is regulated by their mechanical …

β-glycerophosphate, not low magnitude fluid shear stress, increases osteocytogenesis in the osteoblast-to-osteocyte cell line IDG-SW3

R Owen, C Wittkowske, D Lacroix… - Connective Tissue …, 2024 - Taylor & Francis
Aim As osteoblasts deposit a mineralized collagen network, a subpopulation of these cells
differentiates into osteocytes. Biochemical and mechanical stimuli, particularly fluid shear …

[HTML][HTML] Investigation of conjunctival fibrosis response using a 3D glaucoma tenon's capsule+ conjunctival model

R Gater, T Ipek, S Sadiq, D Nguyen… - … & Visual Science, 2019 - tvst.arvojournals.org
Purpose: Surgical techniques such as trabeculectomy aim to treat glaucoma by making an
incision into the scleral tissue, to create an alternative drainage pathway for aqueous to flow …

[HTML][HTML] Preclinical models for in vitro mechanical loading of bone-derived cells

RM Delaine-Smith, B Javaheri, JH Edwards… - BoneKEy …, 2015 - ncbi.nlm.nih.gov
It is well established that bone responds to mechanical stimuli whereby physical forces are
translated into chemical signals between cells, via mechanotransduction. It is difficult …

Inhibition of intimal thickening by PRH (proline-rich homeodomain) in mice

LM Reolizo, H Williams, K Wadey… - … and Vascular Biology, 2023 - Am Heart Assoc
Background: Late vein graft failure is caused by intimal thickening resulting from endothelial
cell (EC) damage and inflammation which promotes vascular smooth muscle cell (VSMC) …

Feline adipose derived multipotent stromal cell transdifferentiation into functional insulin producing cell clusters

T Taguchi, W Duan, W Wolfson, B Duhon… - … in bioengineering and …, 2022 - frontiersin.org
Diabetes mellitus (DM) is one of the most prevalent feline endocrinopathies, affecting up to
1% of pet cats. De novo generation of functional insulin producing cell (IPC) clusters via …

Preclinical models for in vitro mechanical loading of bone-derived cells.

B Javaheri, H Edwards, M Vazquez, RM Rumney - Bonekey Reports, 2015 - europepmc.org
It is well established that bone responds to mechanical stimuli whereby physical forces are
translated into chemical signals between cells, via mechanotransduction. It is difficult …