Organoids are in vitro miniaturized and simplified model systems of organs that have gained
enormous interest for modelling tissue development and disease, and for personalized …

Hepatic, pancreatic, and biliary (HPB) organoids are powerful tools for studying
development, disease, and regeneration. As organoid research expands, the need for clear …

Metabolic diseases, including obesity, diabetes mellitus and cardiovascular disease, are a
major threat to health in the modern world, but efforts to understand the underlying …

Recent advances in 3D cell culture technology have enabled scientists to generate stem cell
derived organoids that recapitulate the structural and functional characteristics of native …

The organoid model represents a major breakthrough in cell biology that has revolutionised
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …

The liver has the ability to repair itself after injury; however, a variety of pathological changes
in the liver can affect its ability to regenerate, and this could lead to liver failure …

Pluripotent stem cell (PSC)-derived organoids have emerged as novel multicellular models
of human tissue development but display immature phenotypes, aberrant tissue fates, and a …

Drug-induced hepatotoxicity is a leading cause of drug withdrawal from the market. High-
throughput screening utilizing in vitro liver models is critical for early-stage liver toxicity …

The bioengineerined and whole matured human brain organoids stand as highly valuable
three-dimensional in vitro brain-mimetic models to recapitulate in vivo brain development …

Liver cancer and disease are among the most socially challenging global health concerns.
Although organ transplantation, surgical resection and anticancer drugs are the main …