Electrical synapses are the neurophysiological product of gap junctional pores between
neurons that allow bidirectional flow of current between neurons. They are expressed …

Learning has been associated with modifications of synaptic and circuit properties, but the
precise changes storing information in mammals have remained largely unclear. We …

In vivo fluorescence recording techniques have produced landmark discoveries in
neuroscience, providing insight into how single cell and circuit-level computations mediate …

Hybrid voltage indicators (HVIs) are chemogenetic sensors that combines the superior
photophysical properties of organic dyes and the genetic targetability of protein sensors to …

The ability to optically image cellular transmembrane voltages at millisecond-timescale
resolutions can offer unprecedented insight into the function of living brains in behaving …

Here we report SUPPORT (statistically unbiased prediction utilizing spatiotemporal
information in imaging data), a self-supervised learning method for removing Poisson …

Electric pulses used in electroporation-based treatments have been shown to affect the
excitability of muscle and neuronal cells. However, understanding the interplay between …

Brain oscillations are crucial for perception, memory, and behavior. Parvalbumin-expressing
(PV) interneurons are critical for these oscillations, but their population dynamics remain …

Fluorescent protein (FP)-based biosensors are genetically encoded tools that enable the
imaging of biological processes in the context of cells, tissues, or live animals. Though …

Functional magnetic resonance imaging (fMRI) with optogenetic neural manipulation is a
powerful tool that enables brain-wide mapping of effective functional networks. To achieve …