The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Leveraging diet to engineer the gut microbiome

M Wolter, ET Grant, M Boudaud, A Steimle… - Nature reviews …, 2021 - nature.com
Autoimmune diseases, including inflammatory bowel disease, multiple sclerosis and
rheumatoid arthritis, have distinct clinical presentations but share underlying patterns of gut …

Fucoidan ameliorated dextran sulfate sodium-induced ulcerative colitis by modulating gut microbiota and bile acid metabolism

X Liu, Y Zhang, W Li, B Zhang, J Yin… - Journal of agricultural …, 2022 - ACS Publications
Gut dysbiosis and bile acid (BA) metabolism disturbance are involved in the pathogenesis of
ulcerative colitis. This study aimed to investigate the effect of fucoidan on BA metabolism …

Involvement of probiotics and postbiotics in the immune system modulation

N Yeşilyurt, B Yılmaz, D Ağagündüz, R Capasso - Biologics, 2021 - mdpi.com
Intestinal microbiota interacts with other systems, especially the immune system, which is
responsible for protecting the body by recognizing “stranger”(pathogen associated …

Fungal microbiome in inflammatory bowel disease: a critical assessment

DM Underhill, J Braun - The Journal of Clinical Investigation, 2022 - Am Soc Clin Investig
The gut microbiome is at the center of inflammatory bowel disease (IBD) pathogenesis and
disease activity. While this has mainly been studied in the context of the bacterial …

Stress triggers flare of inflammatory bowel disease in children and adults

Y Sun, L Li, R Xie, B Wang, K Jiang, H Cao - Frontiers in pediatrics, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease characterized by
chronic and relapsing manifestations. It is noteworthy that the prevalence of IBD is gradually …

A 12‐month pilot study outcomes of vagus nerve stimulation in Crohn's disease

V Sinniger, S Pellissier, F Fauvelle… - …, 2020 - Wiley Online Library
Background The vagus nerve has anti‐inflammatory properties. We aimed to investigate
vagus nerve stimulation (VNS) as a new therapeutic strategy targeting an intrinsic anti …

L-arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut

B Nüse, T Holland, M Rauh, RG Gerlach, J Mattner - Gut Microbes, 2023 - Taylor & Francis
ABSTRACT L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in
mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple …

Improved functionality of Ligilactobacillus salivarius Li01 in alleviating colonic inflammation by layer-by-layer microencapsulation

M Yao, Y Lu, T Zhang, J Xie, S Han, S Zhang… - npj Biofilms and …, 2021 - nature.com
The low viability during gastrointestinal transit and poor mucoadhesion considerably limits
the effectiveness of Ligilactobacillus salivarius Li01 (Li01) in regulating gut microbiota and …

Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbiosis

A Heinken, J Hertel, I Thiele - NPJ systems biology and applications, 2021 - nature.com
Inflammatory bowel diseases, such as Crohn's Disease, are characterised by an altered
blood and faecal metabolome, and changes in gut microbiome composition. Here, we …