Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health
O Babenko, I Kovalchuk, GAS Metz - Neuroscience & Biobehavioral …, 2015 - Elsevier
Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …
stressful experiences during pregnancy exert long-term consequences on the future mental …
Epigenetic basis of mental illness
Psychiatric disorders are complex multifactorial illnesses involving chronic alterations in
neural circuit structure and function as well as likely abnormalities in glial cells. While …
neural circuit structure and function as well as likely abnormalities in glial cells. While …
A data-driven approach to preprocessing Illumina 450K methylation array data
Background As the most stable and experimentally accessible epigenetic mark, DNA
methylation is of great interest to the research community. The landscape of DNA …
methylation is of great interest to the research community. The landscape of DNA …
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is characterized by
progressive neuropathology and cognitive decline. We performed a cross-tissue analysis of …
progressive neuropathology and cognitive decline. We performed a cross-tissue analysis of …
An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation
Background Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by
episodic psychosis and altered cognitive function. Despite success in identifying genetic …
episodic psychosis and altered cognitive function. Despite success in identifying genetic …
Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility
LE Reinius, N Acevedo, M Joerink, G Pershagen… - PloS one, 2012 - journals.plos.org
Methylation of cytosines at CpG sites is a common epigenetic DNA modification that can be
measured by a large number of methods, now even in a genome-wide manner for hundreds …
measured by a large number of methods, now even in a genome-wide manner for hundreds …
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
Age-related changes in DNA methylation have been implicated in cellular senescence and
longevity, yet the causes and functional consequences of these variants remain unclear. To …
longevity, yet the causes and functional consequences of these variants remain unclear. To …
Clashing diagnostic approaches: DSM-ICD versus RDoC
SO Lilienfeld, MT Treadway - Annual review of clinical …, 2016 - annualreviews.org
Since at least the middle of the past century, one overarching model of psychiatric
classification has reigned supreme, namely, that of the Diagnostic and Statistical Manual of …
classification has reigned supreme, namely, that of the Diagnostic and Statistical Manual of …
[图书][B] Behavioral genetics
R Plomin - 2008 - books.google.com
Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …
animal behavioral genetics that is designed to introduce students in the behavioral …
DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia
We performed a systematic analysis of blood DNA methylation profiles from 4483
participants from seven independent cohorts identifying differentially methylated positions …
participants from seven independent cohorts identifying differentially methylated positions …