The concept of developmental origins of diseases has gained a huge interest in recent years
and is a constantly emerging scientific field. First observations hereof originated from …

Many lines of data, initial epidemiologic studies as well as subsequent extensive
experimental studies, indicate that early-life events play a powerful role in influencing later …

Objectives To evaluate the association between paternal obesity and fetal development and
pregnancy complications. Study Design This prospective cohort clinical trial analyzed data …

Background Environmental alternations leading to fetal programming of cardiovascular
diseases in later life have been attributed to maternal factors. However, animal studies …

Abstract Background/Aims: Cardiovascular disease partially originates from poor
environmental and nutritional conditions in early life. Lack of micronutrients like 25 hydroxy …

Background/Aims: Impaired birth outcomes, like low birth weight, have consistently been
associated with increased disease susceptibility to hypertension in later life. Alterations in …

Low birth weight (LBW) is associated with diseases in adulthood. The birthweight attributed
risk is independent of confounding such as gestational age, sex of the newborn but also …

Objective: Fetus with intrauterine stress may exhibit programmed changes that can alter its
metabolism and bear severe risk for diseases in adult life. The current study was designed to …

Background: The renin-angiotensin-aldosterone system (RAAS) is involved in the
pathogenesis of insulin resis-tance and type 2 diabetes in the general population. The …

BECKGROUND: Evaluate the efficacy and safety of telbivudine during the 2nd and 3rd
trimester of pregnancy in intrauterine transmission of hepatitis B virus (HBV). Based on the …