The latest in animal models of pulmonary hypertension and right ventricular failure

O Boucherat, V Agrawal, A Lawrie, S Bonnet - Circulation research, 2022 - Am Heart Assoc
Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …

Pathogenesis of HIV-related lung disease: immunity, infection, and inflammation

SK Cribbs, K Crothers, A Morris - Physiological reviews, 2020 - journals.physiology.org
Despite anti-retroviral therapy (ART), human immunodeficiency virus-1 (HIV)-related
pulmonary disease continues to be a major cause of morbidity and mortality for people living …

Animal models of pulmonary hypertension: Getting to the heart of the problem

JP Dignam, TE Scott, BK Kemp‐Harper… - British Journal of …, 2022 - Wiley Online Library
Despite recent therapeutic advances, pulmonary hypertension (PH) remains a fatal disease
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …

[HTML][HTML] International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): non-proliferative and proliferative lesions of the non-human primate (M …

K Colman, RN Andrews, H Atkins… - Journal of toxicologic …, 2021 - ncbi.nlm.nih.gov
Abstract The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria
for Lesions Project (www. toxpath. org/inhand. asp) is a joint initiative of the Societies of …

Enhanced pulmonary arteriopathy in simian immunodeficiency virus–infected macaques exposed to morphine

L Spikes, P Dalvi, O Tawfik, H Gu… - American journal of …, 2012 - atsjournals.org
Rationale: HIV-associated pulmonary arterial hypertension (PAH) is likely a more prevalent
noninfectious complication of AIDS than previously recognized. Furthermore, the majority of …

Pathogenesis of HIV and the lung

MR Gingo, A Morris - Current HIV/aids Reports, 2013 - Springer
Antiretroviral therapy has improved longevity for HIV-infected persons, but long-term HIV
infection is now complicated by increased rates of chronic medical conditions including …

Human Immunodeficiency Virus nef Signature Sequences Are Associated with Pulmonary Hypertension

S Almodovar, R Knight, AA Allshouse… - AIDS research and …, 2012 - liebertpub.com
Severe pulmonary hypertension (PH) associated with vascular remodeling is a long-term
complication of HIV infection (HIV-PH) affecting 1/200 infected individuals vs. 1/200,000 …

Human immunodeficiency virus–associated pulmonary arterial hypertension: considerations for pulmonary vascular diseases in the developing world

G Butrous - Circulation, 2015 - Am Heart Assoc
Pulmonary hypertension is broadly recognized as a group of disorders that share the
common characteristic of an elevated mean pulmonary arterial pressure (≥ 25 mm Hg) …

Pneumocystis infection and the pathogenesis of chronic obstructive pulmonary disease

KA Norris, A Morris - Immunologic research, 2011 - Springer
With increases in the immunocompromised patient population and aging of the HIV+
population, the risk of serious fungal infections and their complications will continue to rise …

Physiologic changes in a nonhuman primate model of HIV-associated pulmonary arterial hypertension

MP George, HC Champion, M Simon… - American journal of …, 2013 - atsjournals.org
Pulmonary arterial hypertension (PAH) is increased in HIV, but its pathogenesis is not fully
understood. Nonhuman primates infected with simian immunodeficiency virus (SIV) or SIV …