The role of serotonin in depression and antidepressant treatment remains unresolved
despite decades of research. In this paper, we make three major claims. First, serotonin …

Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling)
information from the viscera, skin and other organs is subject to extensive processing by a …

▪ Abstract Motor function is severely disrupted following spinal cord injury (SCI). The spinal
circuitry, however, exhibits a great degree of automaticity and plasticity after an injury …

Although recent evidence demonstrates considerable neuroplasticity in the respiratory
control system, a comprehensive conceptual framework is lacking. Our goals in this review …

The excitability of spinal motoneurons is both fundamental for motor behavior and essential
in diagnosis of neural disorders. There are two mechanisms for altering this excitability. The …

Spinal cord injuries lead to permanent physical impairment despite most often being
anatomically incomplete disruptions of the spinal cord. Remaining connections between the …

Simple Summary Fiber pathways that descend from the brain to the spinal cord drive motor
behavior and modulate incoming sensory signals and the capacity to change (plasticity). A …

Our previous study has reported that electroacupuncture (EA) at low frequency of 2 Hz had
greater and more prolonged analgesic effects on mechanical allodynia and thermal …

Chronic tactile allodynia and hyperalgesia are frequent complications of spinal cord injury
(SCI) with poorly understood mechanisms. Possible causes are plastic changes in the …

Background: Despite the extensive number of studies performed in the last 50 years, aimed
at describing the role of serotonin and its receptors in pain modulation at the spinal cord …