Autophagy is an evolutionarily conserved self-degradation system that recycles cellular
components and damaged organelles, which is critical for the maintenance of cellular …

Colon cancer is one of the major causes of morbidity and mortality worldwide. Dietary
phytochemicals have been drawing increasing attention for colon cancer prevention and …

Medicinal and aromatic plants (MAPs) are known and have been long in use for a variety of
health and cosmetics applications. Potential pharmacological usages that take advantage of …

Colorectal cancer (CRC) is the second most common cancer in females and the third in
males worldwide. Conventional therapy of CRC is limited by severe side effects and by the …

Background Sesquiterpene lactones having α-methylene-γ-lactone moiety are promising
natural metabolites showing various biological activity. One of the major metabolites isolated …

Natural products have long been utilized in traditional medicine as remedies to improve
health and treat illnesses, and have had a key role in modern drug discovery. Recently …

Background Curcumin, a well-studied component in turmeric, exhibits potent antitumor
effects in colorectal cancer. Previous studies showed that turmerones raised the …

In this study, we examined the anti-tumor effects of heat-killed Bifidobacterium and
Lactobacillus strains on human colorectal carcinoma RKO cells in in vitro and in vivo …

An imbalance in the production of reactive oxygen species in the body can cause an
increase of oxidative stress that leads to oxidative damage to cells and tissues, which …

Silymarin, a standardized extract from milk thistle fruits has been found to exhibit anti-cancer
effects against various cancers. Here, we explored the anti-cancer activity of silymarin and …