Biocatalytic Methods for C C Bond Formation

K Fesko, M Gruber‐Khadjawi - ChemCatChem, 2013 - Wiley Online Library
Carbon‐carbon bond formation is among the most challenging transformations in the
organic synthetic chemistry. Enzymes capable to perform this reaction are of great interest …

Terpenoid biosynthesis off the beaten track: unconventional cyclases and their impact on biomimetic synthesis

M Baunach, J Franke… - Angewandte Chemie …, 2015 - Wiley Online Library
Terpene and terpenoid cyclizations are counted among the most complex chemical
reactions occurring in nature and contribute crucially to the tremendous structural diversity of …

Biosynthesis of plant‐derived flavor compounds

W Schwab, R Davidovich‐Rikanati… - The plant …, 2008 - Wiley Online Library
Plants have the capacity to synthesize, accumulate and emit volatiles that may act as aroma
and flavor molecules due to interactions with human receptors. These low‐molecular‐weight …

Characterization of δ-Guaiene Synthases from Cultured Cells of Aquilaria, Responsible for the Formation of the Sesquiterpenes in Agarwood

Y Kumeta, M Ito - Plant Physiology, 2010 - academic.oup.com
The resinous portions of Aquilaria plants, called agarwood, have been used as medicines
and incenses. Agarwood contains a great variety of sesquiterpenes, and a study using …

Diterpene cyclases and the nature of the isoprene fold

R Cao, Y Zhang, FM Mann, C Huang… - Proteins: Structure …, 2010 - Wiley Online Library
The structures and mechanism of action of many terpene cyclases are known, but no
structures of diterpene cyclases have yet been reported. Here, we propose structural models …

Two terpene synthases in resistant Pinus massoniana contribute to defence against Bursaphelenchus xylophilus

B Liu, Q Liu, Z Zhou, H Yin, Y Xie… - Plant, Cell & …, 2021 - Wiley Online Library
Pine wood nematode (PWN; Bursaphelenchus xylophilus), a destructive pest of Pinus
massoniana, is causing a severe epidemic of pine wilt disease in China. When invaded by …

Cloning and Functional Characterization of a β-Pinene Synthase from Artemisia annua That Shows a Circadian Pattern of Expression

S Lu, R Xu, JW Jia, J Pang, SPT Matsuda… - Plant …, 2002 - academic.oup.com
Artemisia annua plants produce a broad range of volatile compounds, including
monoterpenes, which contribute to the characteristic fragrance of this medicinal species. A …

Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis)

SA Green, X Chen, NJ Nieuwenhuizen… - Journal of …, 2012 - academic.oup.com
Flowers of the kiwifruit species Actinidia chinensis produce a mixture of sesquiterpenes
derived from farnesyl diphosphate (FDP) and monoterpenes derived from geranyl …

Secondary metabolites with antimicrobial activity produced by thermophilic bacteria from a high-altitude hydrothermal system

C Pardo-Esté, J Cortés, J Castro-Severyn… - Frontiers in …, 2024 - frontiersin.org
Thermophilic microorganisms possess several adaptations to thrive in high temperature,
which is reflected as biosynthesis of proteins and thermostable molecules, isolation and …

Mutagenesis approaches to deduce structure–function relationships in terpene synthases

MJR Segura, BE Jackson, SPT Matsuda - Natural product reports, 2003 - pubs.rsc.org
Covering: up through 2002This review highlights mutagenesis studies of terpene synthases,
specifically sesquiterpene synthases and oxidosqualene cyclases. Mutagenesis studies of …