Optical super-resolution imaging of surface reactions

T Chen, B Dong, K Chen, F Zhao, X Cheng… - Chemical …, 2017 - ACS Publications
Optical super-resolution imaging has gained momentum in investigations of heterogeneous
and homogeneous chemical reactions at the single-molecule level. Thanks to its exceptional …

Opportunities and challenges in single-molecule and single-particle fluorescence microscopy for mechanistic studies of chemical reactions

T Cordes, SA Blum - Nature chemistry, 2013 - nature.com
In recent years, single-molecule and single-particle fluorescence microscopy has emerged
as a tool to investigate chemical systems. After an initial lag of over a decade with respect to …

Surfactant micellar and vesicle microenvironments and structures under synthetic organic conditions

H Peacock, SA Blum - Journal of the American Chemical Society, 2023 - ACS Publications
Fluorescence lifetime imaging microscopy (FLIM) reveals vesicle sizes, structures,
microenvironments, reagent partitioning, and system evolution with two chemical reactions …

Copper nanoparticle heterogeneous catalytic 'click'cycloaddition confirmed by single-molecule spectroscopy

MR Decan, S Impellizzeri, ML Marin… - Nature …, 2014 - nature.com
Colloidal or heterogeneous nanocatalysts can improve the range and diversity of Cu (I)-
catalysed click reactions and facilitate catalyst separation and reuse. Catalysis by metal …

Role of LiCl in generating soluble organozinc reagents

C Feng, DW Cunningham, QT Easter… - Journal of the American …, 2016 - ACS Publications
The sensitivity provided by fluorescence microscopy enabled the observation of surface
intermediates in the synthesis of soluble organozinc reagents by direct insertion of alkyl …

Variations in Intracellular Organometallic Reaction Frequency Captured by Single‐Molecule Fluorescence Microscopy

D Nguyen, G Yan, TY Chen, LH Do - Angewandte Chemie, 2023 - Wiley Online Library
Studies of organometallic reactions in living cells commonly rely on ensemble‐averaged
measurements, which can obscure the detection of reaction dynamics or location‐specific …

Single-molecule kinetics reveals a hidden surface reaction intermediate in single-nanoparticle catalysis

H Shen, X Zhou, N Zou, P Chen - The Journal of Physical …, 2014 - ACS Publications
Detecting and characterizing reaction intermediates is not only important and powerful for
elucidating reaction mechanisms but also challenging in general because of the low …

Single turnover at molecular polymerization catalysts reveals spatiotemporally resolved reactions

QT Easter, SA Blum - Angewandte Chemie International …, 2017 - Wiley Online Library
Multiple active individual molecular ruthenium catalysts have been pinpointed within
growing polynorbornene, thereby revealing information on the reaction dynamics and …

Organic and organometallic chemistry at the single-molecule,-particle, and-molecular-catalyst-turnover level by fluorescence microscopy

QT Easter, SA Blum - Accounts of Chemical Research, 2019 - ACS Publications
Conspectus Mechanistic studies have historically played a key role in the discovery and
optimization of reactions in organic and organometallic chemistry. However, even …

Exploring chemistry with single-molecule and-particle fluorescence microscopy

O Eivgi, SA Blum - Trends in Chemistry, 2022 - cell.com
The evolution of single-molecule and-particle fluorescence microscopy imaging techniques
for the investigation of chemical reactions has yielded achievements at all fronts, from …