Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

The formation of multicellular microbial communities, called biofilms, starts from the
adhesion of a few planktonic cells to the surface. The transition from a free-living planktonic …

Microorganisms have evolved to thrive in virtually any terrestrial and marine environment,
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …

The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that
regulates many bacterial behaviors and is of key importance for driving the lifestyle switch …

Bacteria have evolved a wide range of sensing systems to appropriately respond to
environmental signals. Here we demonstrate that the opportunistic pathogen Pseudomonas …

Bacteria commonly live attached to surfaces in dense collectives containing billions of cells.
While it is known that motility allows these groups to expand en masse into new territory …

Surface sensing is a critical process that promotes the transition to a biofilm lifestyle. Several
surface-sensing mechanisms have been described for a range of species, most involving …

Chemoreceptors in bacteria detect a variety of signals and feed this information into
chemosensory pathways that represent a major mode of signal transduction. The five …

The opportunistic human pathogen Pseudomonas aeruginosa effectively colonizes host
epithelia using pili as primary adhesins. Here we uncover a surface-specific asymmetric …

Biofilms, which are essential vectors of bacterial survival, protect microbes from antibiotics
and host immune attack and are one of the leading causes that maintain drug-resistant …