With the improvement of nanotechnology and nanomaterials, redox-responsive delivery
systems have been studied extensively in some critical areas, especially in the field of …

In recent years, a range of studies have been conducted with the aim to design and
characterize delivery systems that are able to release multiple therapeutic agents in …

The efficacy of chemotherapy is often reduced due to the chemotherapy resistance of tumor
cells, which is usually caused by abnormal gene overexpression. Herein, multifunctional …

Self-assembled nanostructures that are sensitive to environmental stimuli are promising
nanomaterials for drug delivery. In this class, disulfide-containing redox-sensitive strategies …

Many clinical trials for cancer precision medicine have yielded unsatisfactory results due to
challenges such as drug resistance and low efficacy. Drug resistance is often caused by the …

Synergistic effects of multiple drugs with different modes of action are utilized for
combinatorial chemotherapy of intractable cancers. Translation of in vitro synergistic effects …

Nanotechnology-based combination anticancer therapy offers novel approaches to
overcome the limitations of single-agent administration. The emerging siRNA technology …

Abstract Development of multidrug resistance against antitumor agents is a major limiting
factor for the successful chemotherapy. Currently, both amphiphilic polymeric micelles and …

Transdermal delivery is an attractive delivery method that increases bioavailability, is
suitable for a wide variety of therapeutics, and offers stable delivery outcomes. However …

Gene therapy as a potential method for treatment of genetic disorders and other
malignancies as well as treatment of many cancers has attracted a great amount of attention …