Chagas disease is the most important protozoan infection in the Americas, and constitutes a
significant public health concern throughout the world. Development of new medications …

While prevention is a bedrock of public health, innovative therapeutics are needed to
complement the armamentarium of interventions required to achieve disease control and …

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects millions of
people in the Americas and across the world, leading to considerable morbidity and …

Introduction Chagas disease (CD) imposes social and economic burdens, yet the available
treatments have limited efficacy in the disease's chronic phase and cause serious adverse …

There is an urgent need for new treatments for Chagas disease, a parasitic infection which
mostly impacts South and Central America. We previously reported on the discovery of …

Background More than six million people worldwide, particularly in vulnerable communities
in Latin America, are infected with Trypanosoma cruzi, the causative agent of Chagas …

Neglected diseases caused by kinetoplastid parasites are a health burden in tropical and
subtropical countries. The need to create safe and effective medicines to improve treatment …

Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is a serious public health problem.
Current treatment is restricted to two drugs, benznidazole and nifurtimox, displaying serious …

Chagas disease (CD), a neglected tropical illness caused by the protozoan Trypanosoma
cruzi, affects more than 6 million people mostly in poor areas of Latin America. CD has two …

Chagas disease is a deadly and centenary neglected disease that is recently surging as a
potential global threat. Approximately 30% of infected individuals develop chronic Chagas …