Marine cyanobacteria and microalgae metabolites—A rich source of potential anticancer drugs

A Mondal, S Bose, S Banerjee, JK Patra, J Malik… - Marine Drugs, 2020 - mdpi.com
Cancer is at present one of the utmost deadly diseases worldwide. Past efforts in cancer
research have focused on natural medicinal products. Over the past decades, a great deal of …

[HTML][HTML] Antibacterial and antiviral metabolites from cyanobacteria: their application and their impact on human health

R Carpine, S Sieber - Current Research in Biotechnology, 2021 - Elsevier
Bacterial and viral infections pose a direct threat to human health due to the increase of drug-
resistant and novel pathogenic strains. Natural products represent a prolific source of …

Recent advances in Stetter reaction and related chemistry: an update

MM Heravi, V Zadsirjan… - Asian Journal of …, 2020 - Wiley Online Library
The Stetter reaction is actually a special C− C bond forming reaction through a 1, 4‐addition
reaction in the presence of nucleophilic catalyst. It involves a reaction between aldehydes …

Cyanobacteria as natural therapeutics and pharmaceutical potential: Role in antitumor activity and as nanovectors

H Qamar, K Hussain, A Soni, A Khan, T Hussain… - Molecules, 2021 - mdpi.com
Cyanobacteria (blue-green microalgae) are ubiquitous, Gram-negative photoautotrophic
prokaryotes. They are considered as one of the most efficient sources of bioactive secondary …

Direct Access to Quinone-Fused 5-Substituted-1, 4-Benzodiazepine Scaffolds from Azidoquinones with/without [1, 2]-Azide-Nitrogen Migration: Mechanistic Insights

A Krishnan, S Kamaraj - The Journal of Organic Chemistry, 2023 - ACS Publications
Seven-membered nitrogen heterocycles have a strong influence in drug discovery due to
their inherent 3D character, which allows the ability to explore a vast conformational space …

Revisiting the role of cyanobacteria-derived metabolites as antimicrobial agent: A 21st century perspective

J Kar, DP Ramrao, R Zomuansangi… - Frontiers in …, 2022 - frontiersin.org
Cyanobacterial species are ancient photodiazotrophs prevalent in freshwater bodies and a
natural reservoir of many metabolites (low to high molecular weight) such as non-ribosomal …

Marine biome-derived secondary metabolites, a class of promising antineoplastic agents: A systematic review on their classification, mechanism of action and future …

A Sugumaran, R Pandiyan, P Kandasamy… - Science of the Total …, 2022 - Elsevier
Cancer is one of the most deadly diseases on the planet. Over the past decades, numerous
antineoplastic compounds have been discovered from natural resources such as medicinal …

A general carbazole synthesis via stitching of indole–ynones with nitromethanes: Application to total synthesis of carbazomycin A, calothrixin B, and staurosporinone

S Singh, R Samineni, S Pabbaraja, G Mehta - Organic letters, 2019 - ACS Publications
A new, one-pot domino benzannulation reaction between indole-3-ynones and various
nitromethane derivatives has been explored for a general entry to diversely functionalized …

Marine natural products with high anticancer activities

D Matulja, K Wittine, N Malatesti… - Current medicinal …, 2020 - ingentaconnect.com
This review covers recent literature from 2012-2019 concerning 170 marine natural products
and their semisynthetic analogues with strong anticancer biological activities. Reports that …

Total syntheses of arcyriaflavin A and calothrixin B using 2, 2′-bisindole-3-acetic acid derivative as a common intermediate

S Lee, KH Kim, CH Cheon - Organic letters, 2017 - ACS Publications
A new protocol for the synthesis of 2, 2′-bisindole-3-acetic acid derivatives from aldimines
derived from 2-aminocinnamic acid derivatives and indole-2-carboxaldehyde was …