Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis

YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …

Diagnosis and management of rheumatoid arthritis: a review

D Aletaha, JS Smolen - Jama, 2018 - jamanetwork.com
Importance Rheumatoid arthritis (RA) occurs in about 5 per 1000 people and can lead to
severe joint damage and disability. Significant progress has been made over the past 2 …

EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris–Part 1: treatment and monitoring recommendations

A Nast, C Smith, PI Spuls, G Avila Valle… - Journal of the …, 2020 - Wiley Online Library
This evidence‐and consensus‐based guideline on the treatment of psoriasis vulgaris was
developed following the EuroGuiDerm Guideline and Consensus Statement Development …

Adverse effects of low-dose methotrexate: a randomized trial

DH Solomon, RJ Glynn, EW Karlson, F Lu… - Annals of internal …, 2020 - acpjournals.org
Background: Low-dose methotrexate (LD-MTX) is the most commonly used drug for
systemic rheumatic diseases worldwide and is the recommended first-line agent for …

Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges

JS Smolen, D Aletaha - Nature Reviews Rheumatology, 2015 - nature.com
Rheumatoid arthritis (RA) is considered a chronic disease that cannot be cured. Biologic
agents have enabled good therapeutic successes; however, the response to biologic …

Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force

JS Smolen, FC Breedveld, GR Burmester… - Annals of the …, 2016 - ard.bmj.com
Background Reaching the therapeutic target of remission or low-disease activity has
improved outcomes in patients with rheumatoid arthritis (RA) significantly. The treat-to-target …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

JS Smolen, R Landewé, FC Breedveld… - Annals of the …, 2014 - ard.bmj.com
In this article, the 2010 European League against Rheumatism (EULAR) recommendations
for the management of rheumatoid arthritis (RA) with synthetic and biological disease …

European S3-guidelines on the systemic treatment of psoriasis vulgaris

D Pathirana, AD Ormerod, P Saiag, C Smith… - Journal of the …, 2009 - art.torvergata.it
European S3-Guidelines on the systemic treatment of psoriasis vulgaris D Pathirana, AD
Ormerod, P Saiag, C Smith, PI Spuls, A Na Page 1 JEADV october 2009, volume 23 …

Mesenchymal stem cell-based therapy for rheumatoid arthritis

M Sarsenova, A Issabekova, S Abisheva… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …

[PDF][PDF] The Disease Activity Score and the EULAR response criteria

J Fransen, P Van Riel - Clinical and experimental rheumatology, 2005 - researchgate.net
In rheumatoid arthritis (RA), inflammato ry activity cannot be measure d using one single
variable. For this reason the Disease Activity Score (DAS) has been developed. The DAS is …