Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus …

R Salpini, S D'Anna, L Benedetti, L Piermatteo… - Frontiers in …, 2022 - frontiersin.org
Chronic infection with Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and
mortality worldwide. HBV-DNA integration into the human genome is recognized as a …

Human microbiomes in cancer development and therapy

C Xia, J Su, C Liu, Z Mai, S Yin, C Yang, L Fu - MedComm, 2023 - Wiley Online Library
Colonies formed by bacteria, archaea, fungi, and viral groups and their genomes,
metabolites, and expressed proteins constitute complex human microbiomes. An increasing …

Prevalence and genomic sequence analysis of domestic cat hepadnavirus in the United States

C Stone, R Petch, RB Gagne, M Nehring, T Tu… - Viruses, 2022 - mdpi.com
Hepadnaviruses are partially double-stranded DNA viruses that infect a variety of species.
The prototypical virus in this family is the human hepatitis B virus, which chronically infects …

Viral biomarkers for hepatitis B virus-related hepatocellular carcinoma occurrence and recurrence

Y Liu, V Veeraraghavan, M Pinkerton, J Fu… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the fourth
leading cause of cancer-related death. The most common risk factor for developing HCC is …

[PDF][PDF] Detection of hepatitis B virus–host junction sequences in urine of infected patients

SY Lin, YP Su, ER Trauger, BP Song… - Hepatology …, 2021 - Wiley Online Library
Integrated hepatitis B virus (HBV) DNA, found in more than 85% of HBV‐associated
hepatocellular carcinomas (HBV‐HCCs), can play a significant role in HBV‐related liver …

Novel Assays to Solve the Clinical and Scientific Challenges of Chronic Hepatitis B

T Tu, H Ajoyan, J George - Clinics in Liver Disease, 2023 - liver.theclinics.com
Chronic Hepatitis B is the most common blood-borne virus infection, affecting 262 million
people worldwide. It is a major cause of liver disease and is responsible for w800, 000 …

Genome‐wide loss‐of‐function genetic screen identifies INSIG2 as the vulnerability of hepatitis B virus‐integrated hepatoma cells

M Fukuoka, T Kodama, K Murai, H Hikita… - Cancer …, 2024 - Wiley Online Library
There are approximately 250 million people chronically infected with hepatitis B virus (HBV)
worldwide. Although HBV is often integrated into the host genome and promotes …

Impact of HBV Integration on Hepatocellular Carcinoma After Long-Term Antiviral Therapy

H Wang, B Hu, H Liang, R Wang, L Wei… - … Journal of General …, 2024 - Taylor & Francis
Purpose Few studies have reported the integrated characteristics of hepatitis B virus (HBV)-
related hepatocellular carcinoma (HCC) after long-term antiviral therapy. This study aimed to …

Interferon-alpha responsible EPN3 regulates hepatitis B virus replication

X Li, Z Wang, W Zhou, X Fu, Y Zhang, Y Sun… - Frontiers in …, 2022 - frontiersin.org
Hepatitis B virus (HBV) infection remains a major health problem worldwide, and the current
antiviral therapy, including nucleoside analogs, cannot achieve life-long cure, and …

The Length and Distribution of Plasma Cell‐Free DNA Fragments in Stroke Patients

X Cui, S Du, H Liu, J Liu, Q Wu, Q Huo… - BioMed Research …, 2020 - Wiley Online Library
A number of studies have shown that plasma cell‐free DNA is closely related to the risk of
stroke, but the fragmentation status of plasma cell‐free DNA and its clinical application value …