[HTML][HTML] Natural small molecules in breast cancer treatment: understandings from a therapeutic viewpoint

MR Islam, F Islam, MH Nafady, M Akter, S Mitra, R Das… - Molecules, 2022 - mdpi.com
Breast cancer (BrCa) is the most common malignancy in women and the second most
significant cause of death from cancer. BrCa is one of the most challenging malignancies to …

[HTML][HTML] Thymoquinone: A novel strategy to combat cancer: A review

M Imran, A Rauf, IA Khan, M Shahbaz… - Biomedicine & …, 2018 - Elsevier
The higher consumption of fruit, herbs, spices, and vegetables is well known and practical
strategy to cure human cancers owing to their presence of bioactive compounds. Among …

[HTML][HTML] Thymoquinone, as an anticancer molecule: from basic research to clinical investigation

MA Khan, M Tania, S Fu, J Fu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Thymoquinone is an anticancer phytochemical commonly found in black cumin. In this
review, we discuss the potential of thymoquinone as anticancer molecule, its mechanism of …

[HTML][HTML] Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

The neuroprotective effects of thymoquinone: a review

T Farkhondeh, S Samarghandian… - Dose …, 2018 - journals.sagepub.com
Thymoquinone (TQ), one of the main components active of Nigella sativa, exhibited very
useful biomedical effects such as anti-inflammatory, antioxidant, antimicrobial, antiparasitic …

[HTML][HTML] Anticancer activity of thymoquinone against breast cancer cells: Mechanisms of action and delivery approaches

H Shabani, MH Karami, J Kolour, Z Sayyahi… - Biomedicine & …, 2023 - Elsevier
The rising incidence of breast cancer has been a significant source of concern in the
medical community. Regarding the adverse effects and consequences of current treatments …

[HTML][HTML] Antitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer

OH Alobaedi, WH Talib, IA Basheti - Asian Pacific journal of tropical …, 2017 - Elsevier
Objective To test the anticancer potential activity of the combination of thymoquinone (TQ)
and resveratrol (RES) against breast cancer in mice. Methods The antiproliferative activity of …

[HTML][HTML] North African medicinal plants traditionally used in cancer therapy

JM Alves-Silva, A Romane, T Efferth… - Frontiers in …, 2017 - frontiersin.org
Background: Cancer is a major cause of mortality worldwide with increasing numbers by the
years. In North Africa, the number of cancer patients is alarming. Also shocking is that a …

A review on possible therapeutic effect of Nigella sativa and thymoquinone in neurodegenerative diseases

S Samarghandian, T Farkhondeh… - CNS & Neurological …, 2018 - ingentaconnect.com
Background & Objective: Medicinal plants have attracted great attention in the recent years
and is increasingly applied instead of the chemical drugs. Several documents showed that …

Thymoquinone-based nanotechnology for cancer therapy: Promises and challenges

F Ballout, Z Habli, ON Rahal, M Fatfat… - Drug discovery today, 2018 - Elsevier
Highlights•Nanoformulations of TQ improve delivery and make clinical translation more
likely.•Thymoquinone nanoparticles hold superior promise when compared with free …