Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Background An increasing number of studies are identifying associations between adverse
childhood experiences (ACEs) and ill health throughout the life course. We aimed to …

Background Adverse childhood experience (ACE) scores have become a common
approach for considering childhood adversities and are highly influential in public policy and …

Importance Associations between adverse childhood experiences (ACEs) and chronic
diseases among middle-aged or older Chinese individuals have not been well documented …

Adverse experiences in childhood and adolescence, defined as subjectively perceived
threats to the safety or security of the child's bodily integrity, family, or social structures, are …

Childhood adversity has been repeatedly and robustly linked to physical and mental illness
across the lifespan. Yet, the biological pathways through which this occurs remain unclear …

Child maltreatment is associated with increased risk of an array of mental and physical
health problems. We reviewed studies examining associations of child maltreatment …

Objective: Adverse childhood experiences may be associated with cardiometabolic
morbidity and mortality in adulthood. There is heterogeneity in this literature regarding the …

Purpose The purpose of the study was to develop a measure of ACEs applicable for young
adolescents in low-and middle-income countries (ACEs) and to analyze the relationships of …

This paper focuses on the social hallmarks of aging including low lifetime socioeconomic
status, adversity in childhood and adulthood, being a member of a minority group, adverse …