Wnts are secreted, lipid-modified proteins that bind to different receptors on the cell surface
to activate canonical or non-canonical Wnt signaling pathways, which control various …

More than 20 million individuals worldwide suffer from congenital or acquired bone defects
annually. The development of bone scaffold materials that simulate natural bone for bone …

Osteomyelitis, a debilitating bone infection, presents considerable clinical challenges due to
its intricate etiology and limited treatment options. Despite strides in surgical and …

Stem cells' self-renewal and multi-lineage differentiation are regulated by a complex network
consisting of signaling factors, chromatin regulators, transcription factors, and non-coding …

Osteoporosis is a prevalent chronic metabolic bone disease that poses a significant risk of
fractures or mortality in elderly individuals. Its pathophysiological basis is often attributed to …

Non-coding RNA (ncRNA) is a type of non-protein-coding RNA molecule transcribed from
the genome which performs broad regulation of a variety of biological functions in human …

Postmenopausal osteoporosis (PMOP) affects hundreds of millions of elderly women
worldwide. The imbalance between osteoblast‐mediated bone formation and osteoclast …

Preeclampsia is a multisystem progressive condition and is one of the most serious
complications of pregnancy. Owing to its unclear pathogenesis, there are no precise and …

Osteoporosis is one of the common orthopaedic diseases, characterised by increased bone
fragility due to reduced bone mass and microstructural degeneration, posing a great threat …

Objectives Osteoarthritis (OA) is the most common joint disease. The occurrence and
progression of OA are regulated by epigenetics. A large number of studies have shown the …