Gene-environment interactions within a precision environmental health framework

AA Motsinger-Reif, DM Reif, FS Akhtari, JS House… - Cell Genomics, 2024 - cell.com
Understanding the complex interplay of genetic and environmental factors in disease
etiology and the role of gene-environment interactions (GEIs) across human development …

[HTML][HTML] Which Factors Influence Healthy Aging? A Lesson from the Longevity Village of Bama in China

W Zhang, Q Huang, Y Kang, H Li, G Tan - Aging and Disease, 2023 - ncbi.nlm.nih.gov
A growing aging population is associated with increasing incidences of aging-related
diseases and socioeconomic burdens. Hence, research into healthy longevity and aging is …

Environmental Exposure Science and Human Health

AM Lavezzi, B Ramos-Molina - International journal of environmental …, 2023 - mdpi.com
Human health and environmental exposure form an inseparable binomial. Humans'
relationships with the environment are indeed a fundamental determinant of their state of …

Polygenic risk of hypertriglyceridemia is modified by BMI

V Esteve-Luque, M Fanlo-Maresma… - International Journal of …, 2022 - mdpi.com
Abstract Background: Genetic risk scores (GRSs) have partially improved the understanding
of the etiology of moderate hypertriglyceridemia (HTG), which until recently was mainly …

[HTML][HTML] Cancer diagnosis by gene-environment interactions via combination of SMOTE-Tomek and overlapped group screening approaches with application to …

JH Wang, CY Liu, YR Min, ZH Wu, PL Hou - Mathematics, 2024 - mdpi.com
The complexity of cancer development involves intricate interactions among multiple
biomarkers, such as gene-environment interactions. Utilizing microarray gene expression …

Gene–environment interaction analysis via deep learning

S Wu, Y Xu, Q Zhang, S Ma - Genetic epidemiology, 2023 - Wiley Online Library
Abstract Gene–environment (G–E) interaction analysis plays an important role in studying
complex diseases. Extensive methodological research has been conducted on G–E …

High-Dimensional Gene–Environment Interaction Analysis

M Wu, Y Li, S Ma - Annual Review of Statistics and Its …, 2024 - annualreviews.org
Beyond the main genetic and environmental effects, gene–environment (G–E) interactions
have been demonstrated to significantly contribute to the development and progression of …

Bayesian variable selection for understanding mixtures in environmental exposures

DR Kowal, M Bravo, H Leong, A Bui… - Statistics in …, 2021 - Wiley Online Library
Social and environmental stressors are crucial factors in child development. However, there
exists a multitude of measurable social and environmental factors—the effects of which may …

Overlapping association signals in the genetics of hair-related phenotypes in humans and their relevance to predictive DNA analysis

E Pośpiech, J Karłowska-Pik, M Kukla-Bartoszek… - Forensic Science …, 2022 - Elsevier
Genetic prediction of different hair phenotypes can help reconstruct the physical appearance
of an individual whose biological sample is analyzed in criminal and identification cases. Up …

A two‐phase epigenome‐wide four‐way gene–smoking interaction study of overall survival for early‐stage non‐small cell lung cancer

L Chen, X Wang, N Xie, Z Zhang, X Xu… - Molecular …, 2025 - Wiley Online Library
High‐order interactions associated with non‐small cell lung cancer (NSCLC) survival may
elucidate underlying molecular mechanisms and identify potential therapeutic targets. Our …