Cardiotoxicity of digitalis glycosides: roles of autonomic pathways, autacoids and ion channels

AT Demiryürek, S Demiryürek - Autonomic and autacoid …, 2005 - Wiley Online Library
Summary 1 Cardiac glycosides have been used for centuries as therapeutic agents for the
treatment of heart diaseases. In patients with heart failure, digoxin and the other glycosides …

[PDF][PDF] Pharmacological inhibition of leukotriene biosynthesis: effects on the heart conductance

M Sanak, J Dropinski, B Sokolowska… - Journal of physiology …, 2010 - researchgate.net
Leukotrienes are lipid mediators produced via 5-lipooxygenase pathway of arachidonic
acid. At least two cysteinylleukotrienes receptors are highly expressed in the heart, including …

Possible contribution of leukotrienes in the arrhythmogenic effects of digoxin on isolated guinea-pig hearts

Ş Gök, S Ülker, A Evinç - Pharmacology, 1998 - karger.com
The effect of a leukotriene D4 (LTD4) receptor antagonist, L-648,051, was investigated in
digoxin-induced cardiac toxicity in isolated guinea-pig hearts (Langendorff preparation) …

Contribution of Eicosanoids in the Heart

KU Malik - Hormones and the Heart in Health and Disease, 1999 - Springer
Over the past three decades, considerable progress has been made in the knowledge of
synthesis and metabolism of eicosanoids, and their physiological and pathophysiological …