The increasing demand for natural products as an alternative therapy for chronic diseases
has encouraged research into the pharmacological importance of bioactive compounds from …

Leishmaniasis and Chagas disease cause great impact on social and economic aspects of
people living in developing countries. The treatments for these diseases are based on the …

Oleanolic acid (OA) is a pentacyclic triterpenoid, abundantly found in plants of the Oleaceae
family, and is well known for its beneficial pharmacological activities. Previously, we …

Background Oleanolic acid (OA) is an active compound found in a variety of medicinal herbs
and plants. Though OA has been widely attributed with a variety of biological activities …

Primary amoebic meningoencephalitis (PAM) is a central nervous system (CNS) disease
caused by Naegleria fowleri that mainly affects children and young adults with fatal …

Naegleria fowleri is the causative agent of a type of encephalitis called Primary Amoebic
Encephalitis (PAM). Almost 98% of PAM cases reported worldwide are fatal and affect …

Background The in vitro activity of the brown seaweed Dictyota spiralis against both
Leishmania amazonensis and Trypanosoma cruzi was evaluated in a previous study …

Lantana camara (L.) is employed by several ethnical groups to treat numerous diseases.
Although there are no ethnomedical reports on its use against leishmaniasis, organic …

Naegleria fowleri is the causative agent the primary amoebic meningoencephalitis (PAM), a
fatal disease in more than the 90% of the reported cases that affects the central nervous …

The current chemotherapy of Acanthamoeba keratitis relies on few drugs with low potential
and limited efficacy, for all this there is an urgent need to identify new classes of anti …