A series of 1, 4-naphthoquinone derivatives containing were synthesized as anti-cancer
agents and the crystal structure of compound 5a was confirmed by X-ray diffraction. In …

The novel N-, O-substituted-5-Nitro-1, 4-naphthoquinones (NQ) as regioisomers were
synthesized by reactions of 2, 3-dichloro-5-nitro-1, 4-naphthoquinone with some …

Quinones are ubiquitous in nature and form one of the largest classes of antitumor agents
approved for clinical use. Naphthoquinones and their derivatives are important in many …

Breast cancer is the most frequently diagnosed cancer in women and the second leading
cause of cancer‐related deaths. Because triple‐negative breast cancer (TNBC) is highly …

Abstract Synthesis of new 1, 4-naphthoquinone derivatives is important in terms of searching
new biologically active substances. In particular, compounds with piperazine and thiol …

The class of quinone compounds are excellent representatives of biologically redox-active
compounds. Electron transfers such as in quinone compounds play important roles in the …

Cancer remains a primary cause of mortality, with over 18.1 million new cases and 9.6
million deaths globally in 2018. Chemotherapy, which utilizes a spectrum of cytotoxic drugs …

The class of quinone compounds are excellent representatives of biologically redox-active
compounds. Electron transfers such as in quinone compounds play important roles in the …

The infrared range information uncovered that the optional amine gathering's carbonyl
oxygen and deprotonated nitrogen particles were answerable for the ligands' chelation ways …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a neuronal and
synaptic loss of the cholinergic system and by the accumulation of amyloid β (Aβ) …