General anaesthesia is usually considered to safely induce a reversible brain state allowing
the performance of surgery under optimal conditions. An increasing number of clinical and …

This review of Alzheimer's disease assembles a variety of findings relevant to the
mechanism of the disease and ties them together using the current understanding of the …

Alzheimer's disease is the most common form of dementia, characterized by two
pathological hallmarks: amyloid-β plaques and neurofibrillary tangles. The amyloid …

Traumatic brain injury (TBI) is an established risk factor for the early development of
dementia, including Alzheimer's disease, and the post-traumatic brain frequently exhibits …

The tauopathy-like phenotype observed in the rTg4510 mouse line, in which human
tauP301L expression specifically within the forebrain can be temporally controlled, has …

Slow paced breathing via heart rate variability (HRV) biofeedback stimulates vagus-nerve
pathways that counter noradrenergic stress and arousal pathways that can influence …

The purpose of this white paper is to provide a succinct summary of the different
experimental approaches that have been used in preclinical post-operative cognitive …

Although previously considered entirely reversible, general anaesthesia is now being
viewed as a potentially significant risk to cognitive performance at both extremes of age. A …

Tau pathology found in Alzheimer's disease (AD) is crucial in cognitive decline.
Epidemiologic evidences support that habitual caffeine intake prevents memory decline …

Peri‐operative neurocognitive disorders are the most common complication experienced by
older individuals undergoing anaesthesia and surgery. Peri‐operative neurocognitive …