Endothelial fluid shear stress sensing in vascular health and disease

N Baeyens, C Bandyopadhyay… - The Journal of …, 2016 - Am Soc Clin Investig
Endothelial cells transduce the frictional force from blood flow (fluid shear stress) into
biochemical signals that regulate gene expression and cell behavior via specialized …

Does low and oscillatory wall shear stress correlate spatially with early atherosclerosis? A systematic review

V Peiffer, SJ Sherwin, PD Weinberg - Cardiovascular research, 2013 - academic.oup.com
Low and oscillatory wall shear stress is widely assumed to play a key role in the initiation
and development of atherosclerosis. Indeed, some studies have relied on the low shear …

Multidirectional wall shear stress promotes advanced coronary plaque development: comparing five shear stress metrics

A Hoogendoorn, AM Kok, EMJ Hartman… - Cardiovascular …, 2020 - academic.oup.com
Aims Atherosclerotic plaque development has been associated with wall shear stress
(WSS). However, the multidirectionality of blood flow, and thus of WSS, is rarely taken into …

Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities

L Zhong, JM Zhang, B Su, RS Tan, JC Allen… - Frontiers in …, 2018 - frontiersin.org
The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to
the challenging field of virtual design and testing of technologies in a patient-specific …

Disturbed flow in radial-cephalic arteriovenous fistulae for haemodialysis: low and oscillating shear stress locates the sites of stenosis

B Ene-Iordache, A Remuzzi - Nephrology Dialysis …, 2012 - academic.oup.com
Background. Despite recent clinical and technological advancements, the vascular access
(VA) for haemodialysis still has significant early failure rates after arteriovenous fistula (AVF) …

A review study on blood in human coronary artery: Numerical approach

R Pandey, M Kumar, J Majdoubi, M Rahimi-Gorji… - Computer methods and …, 2020 - Elsevier
Computational fluid dynamics (CFD) study of blood flow in human coronary artery is one of
the emerging fields of Biomed-ical engineering. In present review paper, Finite Volume …

Perspective on CFD studies of coronary artery disease lesions and hemodynamics: a review

JM Zhang, L Zhong, B Su, M Wan… - … journal for numerical …, 2014 - Wiley Online Library
Coronary artery disease (CAD) is the most common cardiovascular disease. Early diagnosis
of CAD's physiological significance is of utmost importance for guiding individualized risk …

Characterizations and correlations of wall shear stress in aneurysmal flow

A Arzani, SC Shadden - Journal of biomechanical …, 2016 - asmedigitalcollection.asme.org
Wall shear stress (WSS) is one of the most studied hemodynamic parameters, used in
correlating blood flow to various diseases. The pulsatile nature of blood flow, along with the …

[HTML][HTML] Medical image-based computational fluid dynamics and fluid-structure interaction analysis in vascular diseases

Y He, H Northrup, H Le, AK Cheung… - … in Bioengineering and …, 2022 - frontiersin.org
Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …

High shear stress induces atherosclerotic vulnerable plaque formation through angiogenesis

Y Wang, J Qiu, S Luo, X Xie, Y Zheng… - Regenerative …, 2016 - academic.oup.com
Rupture of atherosclerotic plaques causing thrombosis is the main cause of acute coronary
syndrome and ischemic strokes. Inhibition of thrombosis is one of the important tasks …