The large-scale production of plant-derived secondary metabolites (PDSM) in bioreactors to
meet the increasing demand for bioactive compounds for the treatment and prevention of …

Almost all therapeutic proteins are glycosylated, with the carbohydrate component playing a
long-established, substantial role in the safety and pharmacokinetic properties of this …

Plants offer several unique advantages in the production of recombinant pharmaceuticals for
humans and animals. Although numerous recombinant proteins have been expressed in …

Protein PEGylation represents a significant technological advancement in the development
of protein-based therapeutics and is widely used to reduce immunogenicity, enhance …

Recombinant proteins are of paramount importance for research, industrial and medical use.
Numerous expression chassis are available for recombinant protein production, and while …

Paclitaxel (PTX) is a high value plant natural product derived from Taxus (yew) species. This
plant specialized metabolite (PSM) and its derivatives constitute a cornerstone for the …

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) had a profound impact on the world's health and …

Immune checkpoint inhibitors (ICIs) are a class of immunotherapy agents capable of
alleviating the immunosuppressive effects exerted by tumorigenic cells. The programmed …

Neurodegenerative diseases (NDDs) are characterized by the progressive degeneration
and/or loss of neurons belonging to the central nervous system, and represent one of the …

Human erythropoietin (EPO) is a key cytokine in erythropoiesis by regulating differentiation
of erythroid progenitor cells into red blood cells (RBCs). Plant cell cultures are considered as …