Pain is a common symptom among patients with cancer. Adequate pain assessment and
management are critical to improve the quality of life and health outcomes in this population …

Constipation is a heterogeneous, polysymptomatic, multifactorial disease. Acute or transient
constipation can be due to changes in diet, travel or stress, and secondary constipation can …

Every May, Gastroenterology publishes a supplemen-tary issue devoted to a topic of
particular interest to the science and practice of gastroenterology. Through a collaboration …

Poorly controlled pain is a global public health issue. The personal, familial and societal
costs are immeasurable. Only a minority of European patients have access to a …

Objective To formulate timely evidence-based guidelines for the management of opioid-
induced bowel dysfunction. Setting Constipation is a major untoward effect of opioids …

(AGA) on the medical management of opioid-induced constipation. The guideline was
developed by the AGA Institute's Clinical Guidelines Committee and approved by the AGA …

Purpose Opioid-induced constipation (OIC) is a frequent and debilitating adverse effect (AE)
of opioids—common analgesics for cancer pain. We investigated the efficacy and safety of a …

Opioids are potent analgesics used for the treatment of acute and chronic pain. Side-effects
are common and among the most bothersome are those associated with opioid-induced …

Offering expert, comprehensive guidance on the basic science, diagnosis, and treatment of
acute musculoskeletal injuries and post-traumatic reconstructive problems, Skeletal Trauma …

Background Opioid-induced constipation is a frequent side-effect of opioid treatment, and
standard interventions have limited or inconsistent efficacy. This study assessed the efficacy …